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Carl Lovely

Name

[Lovely, Carl]
  • Professor

Biography

Carl is a native of the UK and grew up in the small brewery town of Burton-on-Trent, in central England. He attended The University of Birmingham where he obtained a B.Sc. (Hons) in Chemistry in 1987 and remained there to conduct Ph.D. studies with Professor W. Brian Jennings on oxaziridine chemistry (1990). After a postdoctoral stay, supported by a Royal Society Fellowship at the Organisches-Chemisches Institut der Universität Heidelberg with Prof. Klaus Weinges (1991), he then moved to the US, where he did postdoctoral work first with Prof. Leo Paquette (1992-93, Department of Chemistry) and then Prof. Robert Brueggemeier (1993-96, College of Pharmacy), both at The Ohio State University.  He moved to the University of Texas at Arlington (UTA) as an assistant professor in 1996 and was subsequently promoted to associate professor in 2002, and full professor in 2008. In 2010 he was inducted into the Academy of Distinguished Teachers at UTA, becoming a Distinguished Teaching Professor.  His research interests include the development of synthetic methods for heterocycle synthesis, mostly focused on imidazole chemistry. A second area of activity revolves around the discovery and development of transition metal-mediated and -catalyzed reactions. The overarching goal of this methods development is the application of these new reactions to natural products total synthesis.

Professional Preparation

    • 1987 B.Sc. (Hons) in ChemistryUniversity of Birmingham, UK
    • 1990 Ph.D. in Organic ChemistryUniversity of Birmingham, UK

Appointments

    • Aug 2015 to Present Associate Chairperson
      University of Texas at Arlington   Office of the President   Office of the Provost and Vice President for Academic Affairs   College of Science   Chemistry & Biochemistry
    • Jan 2008 to Present Professor
      University of Texas at Arlington
    • Aug 2014 to Aug 2015 Interim Associate Dean
      University of Texas at Arlington   Office of the President   Office of the Provost and Vice President for Academic Affairs   College of Science
    • Jan 2002 to Jan 2008 Assoc Prof
      University of Texas at Arlington
    • Jan 1996 to Jan 2002 Assist Professor
      University of Texas at Arlington
    • Jan 1993 to Jan 1996 Postdoctoral Fellow
      The Ohio State University
    • Jan 1992 to Jan 1993 Postdoctoral Fellow
      The Ohio State University
    • Jan 1991 to Jan 1991 Postdoctoral Research
      Universität Heidelberg

Memberships

  • Membership
    • Feb 2015 to Present ACS

Research and Expertise

  • Heterocyclic Chemistry

    Our research group has been interested for several years in the development of new methods and strategies for the preparation and functionalization of heterocyclic compounds.  In particular, we have focused our recent efforts on the construction of poly substituted imidazole derivatives and have developed an number of new reactions for their construction and elaboration.  The long term goals of this investigation is to provide the tools to assemble complex and biologically active natural products.  Some of our targets are depicted below.

  • Natural Product Total Synthesis
    Principally driven by the areas described above, we have a long standing interest in the total synthesis of biologically active natural products.  Most of our attention has been directed towards natural products isolated from marine environments, and include the oroidin family of alkaloids and the hamigerans.  Although structurally different, these targets share a common trait, that is we utilize the chemistry discoverec in our laboratories to effect these syntheses. 
  • Transition Metal Catalyzed and Mediated Chemistry

    Our group has two major areas of interest involving the utility of transition metal complexes in organic chemistry.  We have been particularly active in studying new applications of the Pauson-Khand reaction, which is an excellent method for the preparation of cyclopentenones.  Our own contributions have focused on using the intramolecular variant of this reaction for the construction of medium-sized rings.  We discovered that using scaffolding elements with bulky substituents that it is possible to construct cyclopentenones annulated to seven, eight and nine-membered rings.  Using a similar approach, we have also used this tactic to assemble extremely congested cyclopentenones.

    In collaboration with the Dias group at UTA, we have been investigating the catalytic potential of some of the highly electron deficient metal complexes prepared by this group and in particular their carbene transfer chemistry.  In the course of these studies, we have discovered several novel reactions and are presently extending these studies to new substrates and new catalysts.

Publications

      Journal Article 2017
      • “Steric Buttressing in the Pauson-Khand Reactions of Benzyl Enynes” Madu, C.E.; Dias, H.V.R.; Lovely, C.J. Tetrahedron 2017, 73, 6118-6137.

        {Journal Article} [Refereed/Juried]
      2017
      • “Thio Acid-Mediated Conversion of Azides to Amides – Exploratory Studies En Route to Oroidin Alkaloids” Herath, A.K.; Bhandari, M.R.; Gout, D.; Yousufuddin, M.; Lovely, C.J. Tetrahedron Lett. 2017, 58, 3913-3918.

        {Journal Article} [Refereed/Juried]
      2017
      • “Tandem Oxidative Dearomatizing Spirocyclizations of Propargylic Guanidines and Ureas” Singh, R.P.; Das, J.K, Yousufuddin, M.; Gout, D.; Lovely, C.J. Org. Lett. 2017, 19, 4110-4113.

        {Journal Article} [Refereed/Juried]
      2017
      • “An Asymmetric Total Synthesis of Martinellic Acid” Badarinarayana, V.; Mahmud, H.; Lovely, C.J. Heterocycles 2017, 95, 1082-1105. (Invited contribution for Masakatsu Shibasaki Special Issue).

        {Journal Article} [Refereed/Juried]
      2017
      • “Syntheses and Cytotoxicities of Leucetta-derived Natural Products and Analogs” Koswatta, P.B.; Kasiri, S.; Das, J.; Bhan, A.; Lima, H.M.; Garcia-Barboza, B.; Khatibi, N.N.; Yousufuddin, M.; Mandal S.S.; Lovely, C.J. Bioorg. Med. Chem. 2017, 25, 1608-1621.

        {Journal Article} [Refereed/Juried]

      Book Chapter 2016
      • “Isolation, Biosynthesis and Synthesis of the Nagelamides” Das, J.; Bhandari, M.; Lovely, C.J. Studies in Natural Products Chemistry Vol 50, Chapter 10, pp 341-371, edited by Att-ur-Rahman, Elsevier, Amsterdam (2016).

        {Book Chapter} [Refereed/Juried]

      Journal Article 2016
      • “Dearomatizing Spirocyclization Reactions of Propargyl Cyanamides” Singh, R.P.; Spears, J.A.; Dalipe, A.; Yousufuddin, M.; Lovely, C.J. Tetrahedron Lett. 2016, 57, 3096-3099.

        {Journal Article} [Refereed/Juried]

      Journal Article 2015
      • “Studies towards the Leucetta-derived Alkaloids Spirocalcaridine A and B – Possible Biosynthetic Implications” Koswatta, P.B.: Das, J.; Yousufuddin, M.; Lovely, C.J.  Eur. J. Org. Chem. 2015, 2603-2613.

        {Journal Article} [Refereed/Juried]
      2015
      • “Preparation and Diels-Alder Reactions of Heterosubstituted Vinylimidazoles” Ray, A.; Mukherjee, S.; Das, J.; Bhandari, M.K.; Du, H.; Yousufuddin, M.; Lovely, C.J. Tetrahedron Lett. 2015, 56, 3518-3522.

        {Journal Article} [Refereed/Juried]

      Journal Article 2014
      • “Total Synthesis of 7’-Desmethylkealiiquinone 4’-Desmethoxykealiiquinone and 2-Deoxykealiiquinone” Lima, H.M.; Rasapalli, S.; Yousufuddin, M.; Lovely, C.J. J. Org. Chem. 2014, 79, 2481.

        {Journal Article} [Refereed/Juried]

      Journal Article 2013
      • Das, J.; Bhan, A.; Mandal, S.S.; Lovely, C.J.“Total Syntheses and Cytotoxicity of Kealiiquinone, 2-Deoxy-2-aminokealiiquinone and Analogs”  Bioorg. Med. Chem. Lett. 2013, 23, 6183

        {Journal Article} [Refereed/Juried]
      2013
      • Perera, S.; Na, Y.-C.; Doundoulakis, T.; Ngo, V.J.; Feng, Q.; Breitbach, Z.S.; Lovely, C.J.; Armstrong, D.W. "The Enantiomeric Separation of Tetrahydrobenzimidazole Intermediates by HPLC and CE Using Cyclodextrin and Cyclofructan Based Chiral Selectors”  Chirality 2013, 25, 133.

        {Journal Article} [Refereed/Juried]
      2013
      • Sivappa, R.; Kumbam, V.; Dhawane, A.; Golen, J.A.; Lovely, C.J.; Rheingold, A.L. “Total Syntheses of Oroidin, Hymenidin and Clathrodin”  Org. Biomol. Chem. 2013, 11, 4133.

        {Journal Article} [Refereed/Juried]

      Book Chapter 2012
      • “A General Approach to the Leucetta Alkaloids” in “Strategy and Tactics in Organic Synthesis” Vol 8, Chapter 8, pp 199-224, edited by Mike Harmata, Elsevier (2012).

        {Book Chapter} [Non-refereed/non-juried]

      Journal Article 2012
      • Das, J.; Koswatta, P.B.; Jones, J.D.; Yousufuddin, M.; Lovely, C.J. "Total Syntheses of Kealiinines A-C” Org. Lett. 2012, 14, 6210.

        {Journal Article} [Refereed/Juried]
      2012
      •  Lima, H.M.;  Sivappa, R.; Yousufuddin, M.; Lovely, C.J. “Total Synthesis of 7’-Desmethylkealiiquinone”Org. Lett. 2012, 14, 2274.

        {Journal Article} [Refereed/Juried]

      Journal Article 2011
      • Lima, H.M.; Lovely, C.J., "Synthesis of 2-Imidazolones and 2-Iminoimidazoles” Org. Lett. 2011, 13, 5736.
        {Journal Article} [Refereed/Juried]
      2011
      • Lima, H.M.; Garcia-Barboza, B.J.; Khatibi, N.N.; Lovely, C.J. “Total syntheses of Isonaamine C and Isonaamidine E”  Tetrahedron Lett. 2011, 52, 5725.
        {Journal Article} [Refereed/Juried]
      2011
      • Koswatta, P. B.; Lovely, C. J. Structural and Synthetic Aspects of 2-Aminoimidazole Alkaloids from Leucetta and Clathrina Sponges. Nat. Prod. Rep. 2011, 28, 511.
        {Journal Article} [Refereed/Juried]
      2011
      • Bhandari, M. R.; Yousufuddin, M.; Lovely, C. J. A Diversity-Oriented Approach to Pyrrole-Imidazole Alkaloid Frameworks. Org. Lett. 2011, 13, 1382.
        {Journal Article} [Refereed/Juried]
      2011
      • He, Y.; Krishnamoorthy, P.; Lima, H.; Chen, Y.; Wu, H.; Sivappa, R.; Dias, H.V.R.; Lovely, C.J. Intramolecular Diels-Alder Reactions of 4-Vinylimidazoles. Org. Biomol. Chem. 2011, 9, 2685.
        {Journal Article} [Refereed/Juried]

      Book Chapter 2010
      • “Silver Carbenoids” – Chapter 8, pp 229-257 in “Silver in Organic Synthesis” edited by Mike Harmata, Wiley and Sons. (2010).
        {Book Chapter} [Non-refereed/non-juried]

      Journal Article 2010
      • Mukherjee, S.; Sivappa, R.; Yousufuddin, M.; Lovely, C. J. The Total Synthesis of ent-Cyclooroidin. Org. Lett. 2010, 12 (21), 4940
        {Journal Article} [Refereed/Juried]
      2010
      • Panduka, P. B.; Lovely, C. J. Total Synthesis of Naamidine G and 14-methoxynaamidine G. Tetrahedron Lett. 2010, 51, 164.
        {Journal Article} [Refereed/Juried]
      2010
      • Mukherjee, S.; Sivappa, R.; Yousufuddin, M.; Lovely, C. J. An Approach to the Oxazoline Fragment of Nagelamide R. Synlett 2010, 817.
        {Journal Article} [Refereed/Juried]
      2010
      • Lovely, C. J.; Sivappa, R.; Mukherjee, S.; Doundoulakis, T.; Lima, H. M.; Yousufuddin, M. Efficient Preparation of Urocanic Acid Derivatives from Histidine. Heterocycles 2010, 80, 1353.
        {Journal Article} [Refereed/Juried]
      2010
      • Koswatta, P. B.; Lovely, C. J. Concise Total Synthesis of Naamine G and Naamidine H. Chem. Commun. 2010, 45, 2148.
        {Journal Article} [Refereed/Juried]
      2010
      • Breitbach, Z. S.; Feng, Q.; Koswatta, P. B.; Dodbiba, E. Lovely, C.J.; Armstrong, D. W. The enantiomeric separation of 4,5-disubstituted imidazoles by HPLC and CE using cyclodextrin-based chiral selectors. Supramol. Chem. 2010, 22, 758.
        {Journal Article} [Refereed/Juried]

      Journal Article 2009
      • Lovely, C. J.; Flores, J. A.; Meng, X.; Dias, H. V. R. Silver-Catalyzed C-H Insertion Reactions with Donor-Acceptor Diazoacetates. Synlett 2009, 129.
        {Journal Article} [Refereed/Juried]
      2009
      • Flores, J. A.; Badarinarayana, V.; Singh, S.; Lovely, C. J.; Dias, H. V. R. Synthesis and Catalytic Activity of an Electron-Deficient Copper-Ethylene Triazapentadienyl Complex. Dalton Trans. 2009.
        {Journal Article} [Refereed/Juried]
      2009
      • Koswatta, P. B.; Sivappa, R.; Dias, H. V. R.; Lovely, C. J. Total Synthesis of the Leucetta-Derived Alkaloid Calcaridine A. Synthesis 2009, 2970.
        {Journal Article} [Refereed/Juried]
      2009
      • Koswatta, P.; Lovely, C. J. Total Synthesis of Preclathridine A and Clathridine A. Tetrahedron Lett. 2009, 50, 4998.
        {Journal Article} [Refereed/Juried]
      2009
      • Sivappa, R.; Mukherjee, S.; Lovely, C. Studies Toward the Total Synthesis of Oroidin Dimers. Org. Biomol. Chem. 2009, 7, 3215.
        {Journal Article} [Refereed/Juried]
      2009
      • Bhandari, M. R.; Sivappa, R.; Lovely, C. Total Synthesis of the Putative Structure of Nagelamide D. Org. Lett. 2009, 11, 1535.
        {Journal Article} [Refereed/Juried]

      Journal Article 2008
      • Dias, H. V. R.; Lovely, C. Carbonyl and Ethylene Adducts of Coinage Metals Supported by Tris(pyrazolyl)borate Ligands and Silver Mediated Atom Transfer Reactions. J. Chem. Rev. 2008, 108, 3223.
        {Journal Article} [Refereed/Juried]
      2008
      • Koswatta, P. B.; Sivappa, R.; Dias, H. V. R.; Lovely, C. Total Synthesis of (±)-Calcaridine A and (±)-epi-Calcaridine A. J. Org. Lett. 2008, 10, 5055.
        {Journal Article} [Refereed/Juried]
      2008
      • Lovely, C. J.; Badarinarayana, V. Synthetic Studies towards the Martinella Alkaloids. Curr. Org. Chem. 2008, 12, 1431.
        {Journal Article} [Refereed/Juried]

      Journal Article 2007
      • Rasapalli, S.; Koswatta, P.; Lovely, C. J. Tetrahedron Lett. 2007, 48, 5771.
        {Journal Article} [Refereed/Juried]
      2007
      • Sivappa, R.; Hernandez, N. M.; He, Y.; Lovely, C. J. Studies toward the Total Synthesis of Axinellamine and Massadine. Org. Lett. 2007, 9 (3861).
        {Journal Article} [Refereed/Juried]
      2007
      • Madu, C. E.; Lovely, C. J. Steric Promotion of the Intramolecular Pauson-Khand Reactions of Aryl Enynes. Synlett 2007 (2011).
        {Journal Article} [Refereed/Juried]
      2007
      • Madu, C. E.; Seshadri, H.; Lovely, C. J. Steric Buttressing in the Pauson-Khand Reaction of Aryl Enynes. Tetrahedron 2007, 63 (5019).
        {Journal Article} [Refereed/Juried]
      2007
      • Madu, C. E.; Lovely, C. J. A Pauson-Khand Approach to the Hamigerans. Org. Lett. 2007, 9 (4697).
        {Journal Article} [Refereed/Juried]
      2007
      • Chen, Y.; Ekanayake, V.; Lovely, C. J. Ring-Closing Metathesis Reactions of Imidazole Derivatives. Heterocycles 2007, 74, 873.
        {Journal Article} [Refereed/Juried]
      2007
      • Krishnamoorthy, P.; Browning, R. G.; Singh, S.; Sivappa, R.; Lovely, C. J.; Dias, H. V. R. Silver(I)-Catalyzed Preparation and [2,3]-Sigmatropic Rearrangement of Halonium Ylides Derived from Allyl and Propargyl Halides and Alkyl Diazoacetates. Chem. Commun. 2007, 731.
        {Journal Article} [Refereed/Juried]
      2007
      • Lovely, C. J.; Du, H.; Sivappa, R.; Bhandari, M. K.; He, Y.; Dias, H. V. R. Preparation and Diels-Alder Chemistry of 4-Vinylimidazoles. J. Org. Chem. 2007, 72, 3741.
        {Journal Article} [Refereed/Juried]
      2007
      • Badarinarayana, V.; Lovely, C. J. Total Synthesis of (-)-Martinellic Acid. Tetrahedron Lett. 2007, 48 (2607).
        {Journal Article} [Refereed/Juried]
      2007
      • Sivappa, R.; Koswatta, P.; Lovely, C. J. Oxidative Reactions of Tetrahydrobenzimidazole Derivatives with N-Sulfonyloxaziridines. Tetrahedron Lett. 2007, 48 (5771).
        {Journal Article} [Refereed/Juried]

      Journal Article 2006
      • He, Y.; Du, H.; Sivappa, R.; Lovely, C. J. New Methods for Imidazole Functionalization  From Imidazole to Marine Alkaloids. Synlett 2006, 965.
        {Journal Article} [Refereed/Juried]
      2006
      • Lovely, C. J.; He, Y.; Fenton, H. M.; Dias, H. V. R. Investigation of the Bromination of Tetrahydrobenzimidazoles. Heterocycles 2006, 70, 129.
        {Journal Article} [Refereed/Juried]
      2006
      • Krishnamoorthy, P.; Sivappa, R.; Du, H.; Lovely, C. J. Palladium-Catalyzed Substitution Reactions of 4-Allylimidazole Derivatives. Tetrahedron 2006, 62, 10555.
        {Journal Article} [Refereed/Juried]
      2006
      • Lovely, C. J.; He, Y.; Mahmud, H.; Moningka, R.; Dias, H. V. R. Cyclization Reactions of N-Acryloyl-2-Aminobenzaldehyde Derivatives: Formal Total Synthesis of Martinellic Acid. Tetrahedron 2006, 62, 8755.
        {Journal Article} [Refereed/Juried]

      Journal Article 2005
      •  He, Y.; Moningka, R.; Lovely, C. J. Formal Total Synthesis of (±)-Martinellic Acid, Tetrahedron Lett. 2005, 46, 1251.
        {Journal Article} [Refereed/Juried]
      2005
      • Lovely, C. J.; Browning, R. G.; Badarinarayana, V.; Dias, H. V. R. A Silver-Catalyzed Büchner Reaction, Tetrahedron Lett. 2005, 46, 2453.

        {Journal Article} [Refereed/Juried]

      Journal Article 2004
      • He, Y.; Chen, Y.; Du, H.; Schmid, L. A.; Lovely, C. J. A Convenient Synthesis of 1,4-Disubstituted Imidazoles, Tetrahedron Lett. 2004, 45, 5529

        {Journal Article} [Refereed/Juried]
      2004
      • Dias, H. V. R.; Browning, R. G.; Richey, S. A.; Lovely, C. J. Silver(I) Scorpionate Mediated Insertion of Carbenes into Aliphatic C-H Bonds, Organometallics, 2004, 23, 1200.
        {Journal Article} [Refereed/Juried]
      2004
      • Lovely, C. J.; Du, H.; He, Y.; Dias, H. V. R. The Oxidative Rearrangement of Imidazoles with Dimethyldioxirane, Org. Lett. 2004, 6, 735.

        {Journal Article} [Refereed/Juried]
      2004
      • Browning, R. G.; Badarinarayana, V.; Mahmud, H.; Lovely, C. J. Palladium-Catalyzed Aryl-Amidation. Synthesis of Non-Racemic Aryl Lactams, Tetrahedron 2004, 60, 362.

        {Journal Article} [Refereed/Juried]

      Journal Article 2003
      • He, Y.; Chen, Y.; Wu, H.; Lovely, C. J. Intramolecular Diels-Alder Reactions of 4-Vinylimidazoles. Org. Lett. 2003, 5, 3623-3656
        {Journal Article} [Refereed/Juried]
      2003
      • Dias, H. V. R.; Browning, R. G.; Polach, S. A.; Diyabalanage, H.V.; Lovely, C. J. Activation of Alkyl Halides via a Silver-Catalyzed Carbene Insertion Process. J. Am. Chem. Soc. 2003, 125, 9270.
        {Journal Article} [Refereed/Juried]
      2003
      • Lovely, C. J.; Du, H.; Dias, H. V. R. The Regioselective Synthesis of 1-Benzyl- and 1-Methyl-4-vinylimidazole and their Reactions with N-Phenylmaleimide. Heterocycles 2003, 60, 1.
        {Journal Article} [Refereed/Juried]
      2003
      • Chen, Y.; Dias, H. V. R.; Lovely, C. J. Synthesis of Fused Bicyclic Imidazoles via Ring-Closing Metathesis. Tetrahedron Lett. 2003, 44, 1379.
        {Journal Article} [Refereed/Juried]

      Journal Article 2002
      • Dias, H. V. R; Lu, H.-L.; Kim, H.-J.; Polach, S. A.; Goh, T. H. K. K.; Browning, R. G.; Lovely, C. J. Copper(I) Ethylene Adducts and Aziridination Catalysts Based on Fluorinated Tris(pyrazoyl)borates [HB(3-(CF3), 5-(R)Pz)3]- (where R = CF3, Ph, H; Pz =
        {Journal Article} [Refereed/Juried]
      2002
      • He, Y. Mahmud, H.; Wayland, B. R.; Dias, H. V. R.; Lovely, C. J. An Azomethine Ylide-Alkene Cycloaddition Approach to Pyrrolo[3,2-c]quinolones. Tetrahedron Lett. 2002, 43, 1171.
        {Journal Article} [Refereed/Juried]

      Journal Article 2001
      • Browning, R. G; Mahmud, H.; Badarinarayana, V.; Lovely, C. J. Synthesis of Chiral N-Aryl Pyrrolidinones via a Palladium-Catalyzed Cross-Coupling Reaction. Tetrahedron Lett. 2001, 42, 7155.
        {Journal Article} [Refereed/Juried]
      2001
      • Lovely, C. J.; Seshadri, H. Wayland, B. R.; Cordes, A. W. Synthesis of Bridged Medium Sized Rings through the Intramolecular Pauson-Khand Reaction. Org. Lett. 2001, 3, 2607
        {Journal Article} [Refereed/Juried]
      2001
      • Lovely, C. J.; Du, H.; Dias, H. V. R. Synthesis and Diels-Alder Reactions of 4-Vinylimidazoles. Org. Lett. 2001, 3, 1319-1322
        {Journal Article} [Refereed/Juried]
      2001
      • Lovely, C. J.; Mahmud, H.; Dias, H. V. R. An Intramolecular Azomethine Ylide-Alkene Cycloaddition Approach to Pyrrolo[3,2-c]quinolines-Synthesis of a C2-Truncated Martinelline Model. Tetrahedron 2001, 57, 4095.
        {Journal Article} [Refereed/Juried]
      2001
      • Lovely, C. J.; Seshadri, H. Intramolecular Pauson-Khand Reactions of Aromatic Enynes. Synth. Commun. 2001, 31, 2479.
        {Journal Article} [Refereed/Juried]
      2001
      • Brueggemeier, R. W.; Bhat, A. S.; Lovely, C. J.; Coughenour, H. D.; Joomprabutra, S.; Weitzel, S. H.; Vandre, D. D.; Yusuf, F.; Burak, Jr.; W. E. 2-Methoxymethylestradiol: A New 2-Methoxy Estrogen Analog that Exhibits Antiproliferative Activity and Alt
        {Journal Article} [Refereed/Juried]

      Journal Article 2000
      • “The Application of Olefin Cross-Metathesis to Organometallics: The Synthesis of Unsaturated Ferrocenyl Alcohols and Ketones.” Seshadri, H.; Lovely, C.J. Org. Lett. 2000, 2, 327.
        {Journal Article} [Refereed/Juried]

      Journal Article 1999
      • “An Approach to the Pyrroloquinoline Core of Martinelline and Martinellic Acid.” Lovely, C.J.; Mahmud, H. Tetrahedron Lett. 1999, 40, 2079.
        {Journal Article} [Refereed/Juried]

      Journal Article 1997
      • “Biochemistry and Pharmacology of 7±-Substituted Androstenediones as Aromatase Inhibitors.” Brueggemeier, R.W.; O’Reilly, J.M.; Lovely, C.J.; Ward, P.J.; Quinn, A.L.; Baker, D.; Darby, M.V.; Gu, X.-J.; Gilbert, N.E., J. Steroid Biochem. Molec. Biol. 1997, 61, 73-77.
        {Journal Article} [Refereed/Juried]
      1997
      • “Aromatase Inhibition in JAr Choriocarcinoma Cells by 7±-Arylaliphatic Androgens.” Brueggemeier, R.W.; Gilbert, N.E.; Gu, X.-J.; O’Reilly, J.M.; Lovely, C.J. J. Steroid Biochem. Molec. Biol. 1997, 61, 247-254.
        {Journal Article} [Refereed/Juried]
      1997
      • “Synthesis and Biological Evaluation of 4-(Hydroxyalkyl)estradiols and Related Compounds.” Lovely, C.J.; Bhat, A.S.; Gilbert, N.E.; Brueggemeier, R.W. J. Med. Chem. 1997, 40, 3756.
        {Journal Article} [Refereed/Juried]

      Journal Article 1996
      • “2-Hydroxyalkyl Estradiols-Synthesis and Biological Evaluation.” Lovely, C.J.; Gilbert, N.E.; Liberto, M.M.; Sharp, D.W.; Lin, Y.C.; Brueggemeier, R.W. J. Med. Chem. 1996, 39, 1917.
        {Journal Article} [Refereed/Juried]

      Journal Article 1995
      • “Studies Directed Towards the Total Synthesis of Cerorubenic Acid-III.4. Exploration of an Organometallic Approach to Construction of the Eastern Sector.” Paquette, L.A.; Hormuth, S.; Lovely, C.J. J. Org. Chem. 1995, 60, 4813.
        {Journal Article} [Refereed/Juried]

      Journal Article 1994
      • “Synthesis of 2-Substituted Hydroxyalkyl and Aminoalkyl Estradiols.” Lovely, C.J.;Brueggemeier, R.W. Tetrahedron Lett. 1994, 35, 8735.
        {Journal Article} [Refereed/Juried]
      1994
      • “Optically Active N-Phosphinoyloxaziridines: Preparation and Chiral Oxygen Transfer to Prochiral Sulfides.” Jennings, W.B.; Kochanewycz, M.J.; Lovely, C.J.; Boyd, D.R. J. Chem. Soc., Chem. Commun. 1994, 2569.
        {Journal Article} [Refereed/Juried]

      Journal Article 1993
      • “Studies Directed Towards the Total Synthesis of Cerorubenic Acid-III.2. Analysis of the Inability to Realize D Ring Formation by Means of Extra-Annular Robinson Annulation.” Paquette, L.A.; Lasalle, G.Y.; Lovely, C.J. J. Org. Chem. 1993, 58, 4254.
        {Journal Article} [Refereed/Juried]

      Journal Article 1992
      • “The Synthesis of Optically Active P-Phenyl-P-(2,4,6-trimethylphenyl)-phosphinamide.” Hamor, T.A.; Jennings, W.B.; Lovely, C.J.; Reeves, K.A. J. Chem Soc., Perkin Trans. 2 1992, 843.
        {Journal Article} [Refereed/Juried]

      Journal Article 1991
      • “The Titanium Tetrachloride Induced Synthesis of N-Phosphinoyl- and N-Sulphonylimines.” Jennings, W.B.; Lovely, C.J. Tetrahedron, 1991, 47, 5561.
        {Journal Article} [Refereed/Juried]

      Journal Article 1990
      • “Monometallic, Homo- and Heterobimetallic Complexes Based on the Redox Active Tris(3,5-Dimethylpyrazoyl)boratomolybdenum and -tungsten Nitrosyls-1. Meta Substituent Effects on the Reduction Potentials of Monometallic Arylamide Complexes.” Salem, S.S.; Lovely, C.J.; Poole, A.G.R.; Jones, C.J.; McCleverty, J.A. Polyhedron 1990, 9, 527.
        {Journal Article} [Refereed/Juried]

      Journal Article 1988
      • “An Efficient Preparation of N-Phosphinoyl and N-Sulphonyl Imines Directly from Aromatic Aldehydes.” Jennings, W.B.; Lovely, C.J. Tetrahedron Lett. 1988, 29, 3725.
        {Journal Article} [Refereed/Juried]

Support & Funding

This data is entered manually by the author of the profile and may duplicate data in the Sponsored Projects section.
    • June 2012 to May 2015 Total Synthesis of Imidazole-Containing Natural Products sponsored by  - $225000
    • May 2011 to June 2014 Total Synthesis of Marine-Derived Alkaloids of the Nagelamide Family sponsored by  - $242084
    • Jan 2009 to Jan 2012 The Total Synthesis of Marine Alkaloids from the Oroidin and Leucetta Families" sponsored by  - $150000
    • Jan 2009 to Jan 2012 Upgrade of NMR Facilities at UTA for Teaching and Research sponsored by  - $340800
    • Jan 2006 to Jan 2009 "The Total Synthesis of Marine Alkaloids" sponsored by  - $150000
    • Jan 2006 to Jan 2007 "Approaches to Bioactive Aminoimidazole Natural Products" sponsored by  - $140000
    • Jan 2004 to Jan 2008 "Approaches to Bioactive Aminoimidazole Natural Products" sponsored by  - $950000
    • Jan 2003 to Jan 2006 "Synthetic Approaches to Marine Alkaloids" sponsored by  - $150000
    • Jan 2003 to Jan 2006 "Upgrade of a 300 MHz NMR Spectrometer for Teaching and Research" sponsored by  - $164950
    • Jan 2000 to Jan 2003 "The Development of Carbon-Centered Radical Reactions of Organometallics" sponsored by  - $135000
    • Jan 2000 to Jan 2001 "Novel Approaches to Bioactive Aminoimidazole Natural Products" sponsored by  - $131000
    • Jan 1997 to Jan 2000 "Radical Reactions of Organometallics" sponsored by  - $124000
    • Jan 1997 to Jan 1998 "The Synthesis of Martinelline and Martinellic Acid" sponsored by  - $10000

Courses

      • CHEM 4346-101 ADVANCED SYNTHETIC METHODS

        Develop an ability to perform a variety of common synthetic procedures, purification and structural characterization techniques of both organic and inorganic molecules.

        Spring - Regular Academic Session - 2017 Download Syllabus Contact info & Office Hours
      • CHEM 2321-002 Organic Chemistry I

        A comprehensive survey of the chemistry of carbon compounds: their structure, properties, bonding, stereochemistry, reactions, and reaction mechanisms.    An introduction to mass spectrometry, infra-red and nuclear magnetic spectroscopy and its application in structure determination.  A description of carbonyl chemistry and its relevance to biomolecules, amino acids, carbohydrates and lipids.  A description of the chemistry of dienes, benzene and aromatic substitution reactions and the chemistry of amines..

        Spring - Regular Academic Session - 2017 Download Syllabus Contact info & Office Hours
      • CHEM 2321-002 ORGANIC CHEMISTRY
        No Description Provided.
        Fall - Regular Academic Session - 2012 Download Syllabus
      • CHEM 4346-001 ADVANCED SYNTHETIC METHODS
        No Description Provided.
        Fall - Regular Academic Session - 2012 Download Syllabus

Other Service Activities

  • Uncategorized
    • Dec  Service (Current)

      College Research Committee (FEP/FDL)

      College Workload Committee

      College P&T Committee

      Faculty Senate

      University Academic Integrity Committee

Administrative Appointment

  • 2014
    • Sept 2014 to Aug 2015 - Interim Assoc Dean, UT-Arlington   COS