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Juhyun Lee

[Juhyun Lee]

Assistant Professor, Bioengineering
Last Updated: February 12, 2020
about me

Education

Education

    • 2016 PhD in Bioengineering
      Univ of Calif Los Angeles, 2016
    • 2012 MS in Bioengineering
      University Southern California, 2012
    • 2010 BA in Bioengineering (Biomechanics)
      University of Utah, 2010

Licensure and Certifications

Licensure and Certifications

    • 2015 Certified LabVIEW Associate Developer,
    • 2011 Certified SolidWorks Associate,

Appointments

Appointments

    • 2017 to 2017 Postdoctoral Fellow
      Medicine(Cadiology) and Bioengineering, (Los Angeles, CA, United States)

Memberships

    • May 2014 to Present American Heart Association
      Member
    • May 2012 to Present Biomedical Engineering Society
      Member

Awards and Honors

    • Dec  2018 AHA Institutional Research Enhancement Award sponsored by American Heart Association
    • Dec  2018 Career Development Award sponsored by American Heart Association
    • Dec  2018 Faculty Fellow of Department of Bioengineering sponsored by University of Texas at Arlington
    • Jun  2016 Harry M. Showman Prize (Best UCLA Engineering PhD Student of Class of 2016) sponsored by UCLA
    • Apr  2016 Travel Award sponsored by Experimental Biology 2016, Annual Meeting from American Association of Anatomists (AAA)
    • Mar  2016 Notable Korean Scientist sponsored by Biological Research Information Center (BRIC), Korea
    • Mar  2015 Outstanding Paper Award sponsored by 18th International Conference on Transducer 2015
    • Nov  2014 AHA Pre-Doctoral Fellowship sponsored by American Heart Association
    • Oct  2014 Reviewer Choice Award sponsored by Biomedical Engineering Society (BMES) Annual Meeting
    • Oct  2013 Travel Award sponsored by Biomedical Engineering Society (BMES) Annual Meeting
    • Mar  2012 4th Place sponsored by 14th Annual IEEE BME-BIOTECH Contest/Caltech
    • May  2010 Undergraduate Research Scholar Designation (URSD) sponsored by University of Utah

News Articles

News Articles

Support & Funding

Support & Funding

This data is entered manually by the author of the profile and may duplicate data in the Sponsored Projects section.
    • July 2018 to June 2021 Investigating Biomechanical effects of hemodynamics and myocardial contractility on the development of trabeculation sponsored by  - $231000
      (Funded)
    • Apr 2018 to Mar 2019 Biomechanical Effects Activating Endocardial and Myocardial Notch Signaling to Modulate Cardiac Trabeculation sponsored by  - $154000
      (Funded)

Publications

      2019
      • Journal Article
        Cardiac tissue engineering: state-of-the-art methods and outlook
        [Nguyen, AhnH, Marsh, Paul, Schmiess-Heine, Lauren, Burke, PeterJ, Lee, Abraham, Lee, Juhyun, Cao, Hung ]. Journal of Biological Engineering.
      • Journal Article
        Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation
        [Hsu, Jeffrey, Vedula, Vijey, Baek, Kyung In, Chang, Chih-chiang, Chen, Junjie, Chou, Man In , Lam, Jeffrey, Subhedar, Shivani, Wang, Jennifer, Ding, Yichen, Chang, Chih-Chiang, Lee, Juhyun, Demer, Linda, Tintut, Yin, Marsden, Alison, Hsiai1, Tzung]. JCI Insight.
      • Journal Article
        Sub-voxel light-sheet microscopy for high-resolution, high-throughput volumetric imaging of large biomedical specimens
        [Fei, Peng, Nie, Jun, Lee, Juhyun, Ding, Yichen, Li, Shuoran, Zhang, Hao, Hagiwara, Masaya, Yu, Tingting, Segura, Tatiana, Ho, Chih-Ming, Zhu, Dan, Hsiaic, Tzung]. Advanced Photonics.
      2018
      • Journal Article
        Light-sheet Fluorescence Microscopy to Capture 4-Dimensional Images of the Effects of Modulating Shear Stress on the Developing Zebrafish Heart
        [Messerschmidt, Victoria , Bailey, Zach, Baek, Kyung In, Bryant, Richard, Li, Rongsong, Hsiai, Tzung, Lee, Juhyun]. Journal of Visualized Experiments.
      • Journal Article
        Light-sheet Fluorescence Microscopy for the Study of the Murine Heart.
        [Ding, Yichen, Bailey, Zach, Messerschmidt, Victoria, Nie, Jun, Bryant, Richard, Rugonyi, Sandra, Fei, Peng, Lee, Juhyun, Hsiai, Tzung]. Journal of Visualized Experiments.
      • Journal Article
        Light-Sheet Imaging to Elucidate Cardiovascular Injury and Repair
        [Ding, Yichen, Lee, Juhyun, Hsu, JeffreyJ, Chang, Chih-chiang, Baek, Kyung-In, Ranjbarvaziri , Sara, Ardehali, Reza, Packard, ReneR, Hsiai, TzungK]. Current cardiology reports.
      2017
      • Journal Article
        A method to quantify mechanobiologic forces during zebrafish cardiac development using 4-D light sheet imaging and computational modeling
        [Vedula, Vijay, Lee, Juhyun, Xu, Hao, Kuo, C-CJay, Hsiai, TzungK, Marsden, AlisonL]. PLoS Computational Biology. 13(10), e1005828. "Public Library of Science".
      • Journal Article
        A Rapid Capillary-Pressure Driven Micro-Channel to Demonstrate Newtonian Fluid Behavior of Zebrafish Blood at High Shear Rates
        [Lee, Juhyun, Chou, Tzu-Chieh, Kang, Dongyang, Kang, Hanul, Chen, Junjie, Baek, KyungIn, Wang, Wei, Ding, Yichen, Di Carlo, Dino, Tai, Yu-Chong, others]. Scientific Reports. 7, "Nature Publishing Group".
      • Journal Article
        Integrating light-sheet imaging with virtual reality to recapitulate developmental cardiac mechanics
        [Ding, Yichen, Abiri, Arash , Abiri, Parinaz , Li, Shuoran, Chang, Chih-Chiang , Baek, Kyung In , Hsu, JeffreyJ, Sideris, Elias, Li, Yilei, Lee, Juhyun, Segura, Tatiana, Nguyen, ThaoP, Bui, Alexander, Packard, René R. Sevag , Fei, Peng, Hsiai, Tzung K]. JCI Insight.
      • Journal Article
        Light-sheet fluorescence imaging to localize cardiac lineage and protein distribution
        [Ding, Yichen, Lee, Juhyun, Ma, Jianguo, Sung, Kevin, Yokota, Tomohiro Yokota, Singh, Neha , Dooraghi, Mojdeh , Abiri, Parinaz , Wang, Yibin , Kulkarni, RajanP, Nakano, Atsushi , Nguyen, Thao P, Fei, Peng, Hsiai, Tzung K]. Scientific Reports. DOI http://dx.doi.org/10.1038/srep42209
      2016
      • Journal Article
        4-Dimensional light-sheet microscopy to elucidate shear stress modulation of cardiac trabeculation
        [Lee, Juhyun, Fei, Peng, Packard, Ren\'e R Sevag, Kang, Hanul, Xu, Hao, Baek, KyungIn, Jen, Nelson, Chen, Junjie, Yen, Hilary, Kuo, C-CJay, others]. The Journal of Clinical Investigation. 126(5), 1679. "American Society for Clinical Investigation".
      • Journal Article
        Cardiac light-sheet fluorescent microscopy for multi-scale and rapid imaging of architecture and function
        [Fei, Peng, Lee, Juhyun, Packard, Ren\'e R Sevag, Sereti, Konstantina-Ioanna, Xu, Hao, Ma, Jianguo, Ding, Yichen, Kang, Hanul, Chen, Harrison, Sung, Kevin, others]. Scientific Reports. 6, 22489. "Nature Publishing Group".
      • Journal Article
        Compact plane illumination plugin device to enable light sheet fluorescence imaging of multi-cellular organisms on an inverted wide-field microscope
        [Lee, Juhyun, Guan, Zeyi, Jiang, Hao, Dong, Siyan, Jen, Nelson, Hsiai, Tzung, Ho, Chih-Ming, Fei, Peng]. Biomedical Optics Letters. 7(1), 194--208. "Optical Society of America".
      2015
      • Journal Article
        Blood flow modulation of vascular dynamics.
        [Lee, Juhyun, Packard, RR, Hsiai, TzungK]. Current Opinion in Lpidology. 26(5), 376--383. "NIH Public Access".
      • Journal Article
        Disturbed flow induces autophagy, but impairs autophagic flux to perturb mitochondrial homeostasis
        [Li, Rongsong, Jen, Nelson, Wu, Lan, Lee, Juhyun, Fang, Karen, Quigley, Katherine, Lee, Katherine, Wang, Sky, Zhou, Bill, Vergnes, Laurent, others]. Antioxidants & Redox Signaling. 23(15), 1207--1219. "Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA".
      2014
      • Journal Article
        Hemodynamics and ventricular function in a zebrafish model of injury and repair
        [Lee, Juhyun, Cao, Hung, Kang, BongJin, Jen, Nelson, Yu, Fei, Lee, Chia-An, Fei, Peng, Park, Jinhyoung, Bohlool, Shadi, Lash-Rosenberg, Lian, others]. Zebrafish. 11(5), 447--454. "Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA".
      • Journal Article
        Shear stress--activated wnt-angiopoietin-2 signaling recapitulated vascular repair in zebrafish embryos
        [Li, Rongsong, Beebe, Tyler, Jen, Nelson, Yu, Fei, Takabe, Wakako, Harrison, Michael, Cao, Hung, Lee, Juhyun, Yang, Hongbo, Han, Peidong, others]. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA--114. "American Heart Association, Inc.".
      • Journal Article
        Wearable multi-channel microelectrode membranes for elucidating electrophysiological phenotypes of injured myocardium
        [Lee, Juhyun, Cao, Hung, Yu, Fei, Zhao, Yu, Zhang, Xiaoxiao , Tai, Joyce, Darehzereshki, Ali , Bersohn, Malcolm , Lien, Ching-Ling , Chi, NeilC, Tai, Yu-Chong , Hsiai, TzungK]. Integrative Biology.
      • Journal Article
        Stretchable electrochemical impedance sensors for intravascular detection of lipid-rich lesions in New Zealand White rabbits
        [Cao, Hung, Yu, Fei, Zhao, Yu, Lee, Juhyun, Scianmarello, Nick, Dai, Wangde, Jen, Nelson, Beebe, Tyler, Li, Rongsong, Ebrahimi, Ramin, Chang, DonaldS, Mody, FrenyV, Pacella, John, Tai, Yu-Chong, Hsiai, Tzung]. Biosensors and Bioelectronics. 54, 610-616.
      2013
      • Journal Article
        Atrial fibrillation pacing decreases intravascular shear stress in a New Zealand white rabbit model: implications in endothelial function
        [Jen, Nelson, Yu, Fei, Lee, Juhyun, Wasmund, Steve, Dai, Xiaohu, Chen, Christina, Chawareeyawong, Pai, Yang, Yongmo, Li, Rongsong, Hamdan, MohamedH, others]. Biomechanics and Modeling in Mechanobiology. 12(4), 735--745. "Springer-Verlag".
      • Journal Article
        Elevated electrochemical impedance in the endoluminal regions with high shear stress: Implication for assessing lipid-rich atherosclerotic lesions
        [Yu, Fei, Lee, Juhyun, Jen, Nelson, Li, Xiang, Zhang, Qian, Tang, Rui, Zhou, Qifa, Kim, EunS, Hsiai, TzungK]. Biosensors and Bioelectronics. 43, 237--244. "Elsevier".
      • Journal Article
        Moving domain computational fluid dynamics to interface with an embryonic model of cardiac morphogenesis
        [Lee, Juhyun, Moghadam, MahdiEsmaily, Kung, Ethan, Cao, Hung, Beebe, Tyler, Miller, Yury, Roman, BethL, Lien, Ching-Ling, Chi, NeilC, Marsden, AlisonL, others]. PLoS One. 8(8), e72924. "Public Library of Science".
      2012
      • Journal Article
        A dynamic model of calcific nodule destabilization in response to monocyte-and oxidized lipid-induced matrix metalloproteinases
        [Li, Rongsong, Mittelstein, David, Lee, Juhyun, Fang, Karen, Majumdar, Rohit, Tintut, Yin, Demer, LindaL, Hsiai, TzungK]. American Journal of Physiology. Cell Physiology. 302(4), C658--C665. "Am Physiological Soc".
      2018
      • Conference Proceeding
        Integrating 4-d light-sheet imaging with interactive virtual reality to recapitulate developmental cardiac mechanics and physiology
        [Ding, Yichen, Yu, Jing, Abiri, Arash, Lee, Juhyun, Chang, Chih-chiang, Baek, Kyung In, Packard, ReneR, Hsiai, Tzung, , , , , Hsiai, K]. International Society for Optics and Photonics.
      2017
      • Conference Proceeding
        A vacuum capillary viscometer that measures the viscosity of biofluids
        Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), 2017 19th International Conference on
        [Chou, Tzu-Chieh, Lee, Juhyun, Hsiai, TzungK, Tai, Yu-Chong]. 1547--1550.
      2015
      • Conference Proceeding
        Flexible micro sensor for intravascular vulnerable plaque diagnostic with electrical impedance spectroscopy
        Nano/Micro Engineered and Molecular Systems (NEMS), 2015 IEEE 10th International Conference on
        [Zhang, Xiaoxiao, Xu, Lei, Lee, Juhyun, Li, Rongsong, Liu, Yang, Shapero, Aubrey, Hsiai, Tzung, Tai, Yu-Chong]. 243--247.
      • Conference Proceeding
        Measurement of viscosity of adult zebrafish blood using a capillary pressure-driven viscometer
        Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), 2015 Transducers-2015 18th International Conference on
        [Kang, D, Wang, W, Lee, Juhyun, Tai, YC, Hsiai, TK]. 1661--1664.

Presentations

    •  2019
      Lee, Juhyun, "Heart Development in Cardiac Mechanics", Health Occupational Students of America (HOSA) Meeting, Arlington. ( , 2019).
    •  2019
      Lee, Juhyun, "Integrating advanced imaging and nanoparticles to study cardiac chamber development", Korea Tissue Engineering Regenerative Medicine Society (KTERMS), Jeju, Korea. ( , 2019).
    •  2018
      Lee, Juhyun (Presenter), "4-D Hemodynamic Forces Regulate Trabeculation and Consequent Cardiac Function during Development", Atlanta, GA. ( , 2018).
    •  2018
      Lee, Juhyun, "Integrating Light-Sheet Imaging and Hemodynamic Shear Forces to Study Developmental Cardiac Mechanics", University of Texas at Arlington, Arlington. ( , 2018).
    • November  2017
      Lee, Juhyun, Vedula, Vijay, Marsden, AlisonL, Hsiai, TzungK, "Spatiotemporal Variations in Intracardiac Shear Stress Differentially Modulate Trabeculation for Developmental Contractile Function", American Heart Association, Anaheim, CA. (November 14, 2017).
    • October  2017
      Lee, Juhyun, "Integrating Light-Sheet Imaging and Hemodynamic Shear Forces to Study Developmental Cardiac Mechanics", IEEE , Arlington, TX. (October 26, 2017).
    • October  2017
      Lee, Juhyun, Vedula, Vijay, Chen, Junjie, Hsu, Jeffrey, Marsden, Alison, Hsiai, Tzung, "Spatiotemporal Variations in Intracardiac Shear Stress Differentially Modulate Trabeculation for Developmental Contractile Function", Biomedical Engineering Society, Phoenix, AZ. (October 13, 2017).
    • October  2016
      Lee, Juhyun, Kang, Dongyang, Jen, Nelsong, Di Carlo, Dino, Tai, Yu-Chong, Hsiai, TzungK, "Capillary pressure-driven micro-viscometer to quantify a living zebrafish fluidic system", Biomedical Engineering Society, Minneapolis, MN. (October 6, 2016).
    • April  2016
      Lee, Juhyun, Packard, ReneRP, Xu, Hao, Kang, Hanul, Baek, Kyung In, Jen, Nelson, Kuo, C.-C.J, Chi, NeilC, Ho, Chih-Ming, Hsiai, TzungK, "Light-Sheet Microscopy to Elucidate Hemodynamic Forces and Modulation of Cardiac Trabeculation: Implications for Embryonic Contractile Function", San Diego, CA. (April 3, 2016).
    • October  2015
      Lee, Juhyun, Fei, Peng, Xu, Hao, Kuo, C.-C.J, Yelon, Deborah, Ho, Chih-Ming, Hsiai, TzungK, "Light-Sheet Microscopy to Elucidate Hemodynamic Forces and Modulation of Cardiac Trabeculation: Implications for Embryonic Contractile Function", Biomedical Engineering Society, Tampa, FL. (October 9, 2015).
    • November  2014
      Lee, Juhyun, Fei, Peng, Jen, Nelson, Beebe, Tyler, Ho, Chih-Ming, Marsden, AlisonL, Chi, NeilC, Hsiai, TzungK, "Novel 4-Dimensional Optical Technique to Elucidate Hemodynamic Shear Forces and Initiation of Trabeculation During Cardiac Morphogenesis", American Heart Association, Chicago, IL. (November 17, 2014).
    • October  2014
      Lee, Juhyun, Fei, Peng, Xu, Hao, Li, Rongsong, Kuo, JayC.-C., Hsiai, TzungK, "Linking between cardiac trabeculation development and wall shear stress with 4-Dimensional Single Plane Illumination Microscopy", San Antonio, TX. (October 23, 2014).
    • April  2014
      Lee, Juhyun, Fei, Peng, Xu, Hao, Li, Rongsong, Kuo, JayC.-C., Ho, Chih-Ming, Chi, NeilC, Hsiai, Tzung K, "Linking wall shear stress with cardiac trabeculation in zebrafish", San Diego, CA. (April 27, 2014).
    • October  2013
      Lee, Juhyun, Cao, Hung, Esmaily-Moghadam , Mahdi, Kung, EthanO, Marsden, AlisonL, Hsiai, TzungK, "Moving Domain Computational Fluid Dynamics to Interface with An Embryonic Model of Cardiac Morphogenesis". (October 26, 2013).
    • April  2013
      Lee, Juhyun, Cao, Hung, Hsiai, Tzung K, "Study of Zebrafish Cardiac Morphogenesis Using Computational Fluid Dynamics", Boston, MA. (April 24, 2013).
    • April  2012
      Lee, Juhyun, Jen, Nelson, Yu, Fei, Dai, Wangde, Yu, Hongyu, Hsiai, Tzung K , "Flexible Intravascular thermal sensor to assess atherosclerosis-mediated changes in hemodynamics", Atlanta, GA. (April 26, 2012).
    • April  2010
      Lee, Juhyun, Monson, KennethL, "Determining mechanical properties of blood vessels in neonates for understanding the Intraventricular Hemorrhaging". (April 5, 2010).

Students Supervised

    • May 2019
      Tingfeng Yao, (Bioengineering)
    • Nov 2017
      Sarmishtha Satpathy, (Electrical Engineering)

Courses

      • BE 3320-023 MEASUREMENT LABORATORY
        (Course Id: 111651)
        Spring - Regular Academic Session - 2020 Download Syllabus
      • BE 6297-023 RESEARCH IN BIOENGINEERING
        (Course Id: 102117)
        Spring - Regular Academic Session - 2020
      • BE 6397-023 RESEARCH IN BIOENGINEERING
        (Course Id: 102121)
        Spring - Regular Academic Session - 2020
      • BE 6997-023 RESEARCH IN BIOENGINEERING
        (Course Id: 102130)
        Spring - Regular Academic Session - 2020
      • BE 3320-023 MEASUREMENT LABORATORY
        (Course Id: 111651)
        Fall - Regular Academic Session - 2019 Download Syllabus
      • BE 6297-023 RESEARCH IN BIOENGINEERING
        (Course Id: 102117)
        Fall - Regular Academic Session - 2019
      • BE 6397-023 RESEARCH IN BIOENGINEERING
        (Course Id: 102121)
        Fall - Regular Academic Session - 2019
      • BE 3320-023 MEASUREMENT LABORATORY
        (Course Id: 111651)
        Spring - Regular Academic Session - 2019 Download Syllabus
      • BE 6397-023 RESEARCH IN BIOENGINEERING
        (Course Id: 102121)
        Spring - Regular Academic Session - 2019
      • BE 3320-023 MEASUREMENT LABORATORY
        (Course Id: 111651)
        Fall - Regular Academic Session - 2018 Download Syllabus
      • BE 6103-023 PhD SEMINAR IN BIOENGINEERING
        (Course Id: 102112)
        Fall - Regular Academic Session - 2018
      • BE 6297-023 RESEARCH IN BIOENGINEERING
        (Course Id: 102117)
        Fall - Regular Academic Session - 2018
      • BE 6397-023 RESEARCH IN BIOENGINEERING
        (Course Id: 102121)
        Summer - Eleven Week - 2018
      • BE 3310-020 BIOMECHANICS AND FLUID FLOW
        (Course Id: 111687)
        Spring - Regular Academic Session - 2018
      • BE 3310-023 BIOMECHANICS AND FLUID FLOW
        (Course Id: 111687)
        Spring - Regular Academic Session - 2018 Download Syllabus
      • BE 5310-023 BIOMECHANICS AND FLUID FLOW
        (Course Id: 112491)
        Spring - Regular Academic Session - 2018 Download Syllabus
      • BE 6397-023 RESEARCH IN BIOENGINEERING
        (Course Id: 102121)
        Spring - Regular Academic Session - 2018
      • BE 6397-023 RESEARCH IN BIOENGINEERING
        (Course Id: 102121)
        Fall - Regular Academic Session - 2017

Service to the University

    • 2019 to  Present Faculty Mentor
      Honors College Undergraduate Research Fellowship
      Mentoring Bijan Gaire
    • 2019 to  Present Faculty Mentor
      I-Engage Program
      Mentoring Jessica Lim
    • 2018 to  Present Committee Member
      PhD Diagnostic Exam Committee member, Imaging Track
    • 2018 to  Present Committee Member
      PhD Diagnostic Exam Committee member, Tissue Engineering Track

Service to the Profession

    • 2019 to  Present
      Reviewer, Journal Article
      Scientific Reports
    • 2019 to  Present
      Reviewer, Journal Article
      Sensor & Actuators: A. Physical
    • 2019 to  Present
      Reviewer, Journal Article
      Small
    • 2018 to  Present
      Reviewer, Journal Article
      Mediators of Inflammation
    • 2018 to  Present
      Reviewer, Journal Article
      Sensors
    • 2017 to  Present
      Reviewer, Journal Article
      PLOS One

Service to the Community

Service to the Community

    • 2017 to  Present
      Program Coordinator
      Summer Research for High School Student
      Karina Tacconi (Martin High School, Arlington ISD, TX) Alec Kramer (Marcus High School, Lewisville ISD, TX) Ashley Chuong (Lake Ridge High School, Mansfield ISD, TX) Ryan Lee (Flower Mound High School, Lewisville ISD, TX) Atulya Palacharla (Plano East Senior High School, Plano ISD, TX) Ryan Lee (Flower Mound High School, Lewisville ISD, TX) Atulya Palacharla (Plano East Senior High School, Plano ISD, TX)
    • Oct 2019 to  Oct 2019
      Session Chair
      BMES conference Stem Cells in Tissue Engineering session