Liping Tang
Name
[Tang, Liping]
- Professor
Biography
Dr. Liping Tang received his Ph.D. degree in Biomedical Engineering and Chemical Engineering from University of Minnesota. After completion of post-doctoral training at Albany Medical College, he became an Assistant Professor at the Department of Pediatrics at Baylor College of Medicine, Houston, Texas. Currently, he is a Professor at the Department of Bioengineering at UTA. His research interest is to understand the mechanism of foreign body reactions. Using various in vivo imaging techniques, his group is actively working on the development of various imaging probes to monitor different processes and stages of foreign body reactions.
By applying the knowledge generated by these fundamental researches, his group is actively working on the development of bioactive materials and drug delivery nanomaterials which enhance tissue regeneration associated with a variety of diseases. As the results of these efforts, his group has recent discovered that biomaterial implants could prompt the recruitment and accumulation of a variety of progenitor cells, including mesenchymal stem cells. Using scaffolds to release a variety of chemokines and differentiation agents, his laboratory has developed the “Induced Regeneration via Autologous Stem Cell Regeneration (IRASC) technology which serves as the foundation of this proposed work.
His expertise covers a broad area of stem cells, tissue engineering, nanotechnology, biocompatibility, biomaterials, inflammation, infection and fibrosis. He has published many of his work in high impact journals, including Biomaterials, Journal of Clinical Investigation, Proceeding of National Academy of Science USA, Blood, Journal of Experimental Medicine, and Tissue Engineering. Many of his papers received high reference citations (11 papers with citation >100). His research is currently supported by funding from NIH and several medical device companies. He is the recipient of the Young Investigator Award from the Society for Biomaterials on 2001, Established Investigator Award from the National American Heart Association in 2003, and UTA College of Engineering Excellence in Research Award in 2010. He is recently elected as Fellow of the American Heart Association, Fellow of Biomaterials Science and Engineering and Fellow of the American Institute for Medical and Biological Engineering. He also serves as an active member on several NIH study sections.
Professional Preparation
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- 1986 B.S. in Biology , Tunghai University, Taichung, Taiwan
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- 1988 MS in Marine Biology , National Taiwan University, Taipei, Taiwan
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- 1992 PhD in Biomedical Engineering (Chemical Engineering), University of Minnesota
Appointments
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June 2013 to
Present
Visiting Professor
Kaohsiung Medical University, Taiwan -
June 2013 to
June 2015
Interim Chair of Bioengineering
University of Texas at Arlington
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June 2013 to
Present
Visiting Professor
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Sept 2007 to
Present
Professor
University of Texas at Arlington
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Sept 2007 to
Present
Professor
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Sept 2000 to
Aug 2007
Associate Professor
University of Texas at Arlington
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Sept 2000 to
Aug 2007
Associate Professor
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Jan 1996 to
Aug 2000
Assistant Professor
Albany Medical College Medical College Baylor College of Medicine
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Jan 1996 to
Aug 2000
Assistant Professor
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Jan 1995 to
May 1996
Assistant Professor
Albany Medical College
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Jan 1995 to
May 1996
Assistant Professor
Memberships
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Membership
- Aug 2010 to Present Biomedical Engineering Society
- Sept 2009 to Present Society of Toxicology
- May 2005 to Present Chinese Institute of Engineering
- Sept 2003 to Present Controlled Release Society
- Nov 2000 to Present The Association for Research in Vision and Ophthalmology
- Sept 2000 to Present American Association for The Advance of Science
- May 1995 to Present Society of Chinese Bioscientists in America
- June 1994 to Present American Heart Association (AHA)
- May 1993 to Present Society for Biomaterials
Awards and Honors
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- Sep 2014 Awardee College of Engineering Research Excellence Award, 2005-2007 sponsored by The University of Texas Arlington
- Apr 2014 UT Arlington Academy of Distinguished Scholars sponsored by University of Texas at Arlington
- Jan 2014 Recipient of Research Fund of International Young Scientists (2014-2015) sponsored by National Natural Science Foundation of China
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- Apr 2013 Outstanding Academic Advisorv- Graduate Faculty sponsored by University of Texas at Arlington
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- Sep 2012 Elected as Eminent Engineer of Tau Beta Pi sponsored by The Engineering Honor Society, Texas ETA Chapter, Arlington, Texas
- Jun 2012 Elected Steering Committee Member sponsored by International College of Fellows-Bilmaterials Science and Engineering (ICF-BSE)
- May 2012 Keynote Speaker at the Scandinavian Society of Biomaterials Meeting sponsored by Scandinavian Society for Biomaterials Uppsala, Sweden
- May 2012 Fellow of Biomaterials Science and Engineering sponsored by International Union of Society for Biomaterials Science and Engineering
- May 2012 Invited Chair Professor sponsored by National Changhua Univerity of Education, Changhua, Taiwan
- Apr 2012 Honorable Mention, Outstanding Academic Advisor Award sponsored by University of Texas at Arlington
- Apr 2012 Outstanding Research Achievement Award sponsored by University of Texas at Arlington
- Apr 2012 Outstanding Fair Director 2010-2012 Award sponsored by Fort Worth Regional Science and Engineering Fair
- Feb 2012 Fellow of the American Insttitute for Medical and BIological Engineering sponsored by American Institute for Medical and Biological Engineering
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- Sep 2011 Track Organizer and Session Chair for 27th Southern Biomedical Engineering Conference sponsored by Southern Biomedical Engineering Conference Arlingon, Texas
- Jul 2011 Fellow of the American Heart Association sponsored by American Heart Association (AHA)
- Apr 2011 Wayne Barcellona Award sponsored by Fort Worth Regional Science and Engineering Fair
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- Jun 2010 Appointed as Visiting Professor (research) sponsored by College of Life Science, Kaohsiung Medical University, Kaosiung, Taiwan
- Feb 2010 College of Engineering Excellence in Research Award sponsored by University of Texas at Arlington
- Jan 2010 Mentor Recognition, Siemens Foundation, Jan. 21 2011. sponsored by Siemens Foundation
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- Sep 2009 2009 Phi Kappa Phi Recognized Professor sponsored by UT Arlington’s Chapter of The Honor Society of Phi Kappa Phi
- Sep 2009 College of Engineering Research Excellence Award sponsored by University of Texas at Arlington
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- Sep 2008 Recipient of the Faculty Development Leave Award sponsored by University of Texas at Arlington
- Sep 2008 Research Excellent Award in the College of Engineering sponsored by University of Texas at Arlington
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- Sep 2007 Awardee College of Engineering Research Excellence Award, 2005-2007 sponsored by University of Texas at Arlington
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- Sep 2006 Awardee College of Engineering Research Excellence Award, 2005-2007 sponsored by University of Texas at Arlington
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- Aug 2005 Invited Plenary Speaker sponsored by Chinese Institute of Engineering
- Aug 2005 Awardee College of Engineering Research Excellence Award, 2005-2007 sponsored by University of Texas at Arlington
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- Aug 2002 Invited Plenary Speaker sponsored by Chinese Institute of Engineering
- Apr 2002 Established Investigator Award sponsored by National American Heart Association
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- Apr 2001 2001, Young Investigator Award from Society for Biomaterials sponsored by Society for Biomaterials
News Articles
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Apr 2014 Student eats his way to success
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Research and Expertise
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ResearchHis research interest covers the following areas- stem cell tissue engineering, nanoparticle drug delivery, cancer therapy and in vivo imaging.
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Research Innovation
Dr. Tang’s laboratory has discovered and established many new technologies which are summarized in the following.
- New imaging tools. Almost all medical device development relies on the use of animal models to assess the immune reactions to the implants which are expensive and time consuming. To overcome such challenges, Dr. Tang’s laboratory has recently invented a new imaging technology platform which permits a real time monitoring of foreign body reactions. This system will expedite the development of safe and effective medical implants. The contribution of this work is widely recognized. As a result of this recognition, Dr. Tang has been invited to present this work and to give keynote speeches at many international conferences, including Society for Biomaterials’ meetings, Biomedical Engineering Society meetings, American Heart Association’s meetings, and Meeting of the Scandinavian Society for Biomaterials.
- Novel autologous stem cell therapy. Dr. Tang’s research on foreign body reactions has led to the discovery of a new method to recruit large numbers of autologous stem cells in animals. This method has also been demonstrated to collect large numbers of functional stem cells in human patients. By taking advantage of this discovery, Dr. Tang’s group has developed a patentable method in which autologous stem cells can be recruited to the injured tissue via tissue scaffolds releasing specific chemical signals. This new method is currently undergoing human trial at University of Texas Southwestern Medical Center’s peritoneal dialysis center. Recent studies have shown that the stem cell therapy has great promise in curing diabetes.
- Novel anti-osteoporosis treatment. Dr. Tang’s recent studies have also discovered that the impaired function of stem cells’ regenerative activities is responsible for the ageing processes – deterioration of the normal tissue, such as bone and muscles. His group found that the transplantation of young and healthy stem cells is sufficient to delay ageing of bone and prolongs the lifespan of old animals by >15%. This discovery revolutionizes the general concept and approach in ageing research and stem cell therapy. This discovery was highlighted in the Nature news website and several scientific discovery websites.
- New therapy for combating metastasis cancer. By incorporating newly identified factors with tissue scaffolds, Dr. Tang has invented a “cancer trap” implant which can recruit and eliminate circulating metastatic cancer cells in animals. This new invention has proven to be effective to extend the lifetime of the cancer bearing animals by 20%. The development of the cancer trap is currently funded by the Cancer Prevention & Research Institute of Texas (Dec, 2011). A patent application to cover this technology has been recently submitted and sponsored by UTA.
Publications
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{Journal Article }
Shen J, Zheng J, Saxena R, Zhang CC, Tang L. Characterization of human hematopoietic stem cells from peritoneal dialysis effluents. Stem Cells Research (in revision), 2015.
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{Journal Article }
Di Y, Tian C, Feng S, Chen D, Wang Q, Cui S, Tang L, Gu Y. Multifunctional gold nanorod-loaded microcapsules for targeting and controlled drug delivery on tumor (in submission), 2015.
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{Journal Article }
Shen J, Saxena R, Kamath S, Borchardt J, Zhang CC, Tang L. Adult stem cells recruited in response to inflammation. (in submission), 2015.
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{Journal Article }
Weng H, Zhou J, Tang L. Molecular basis of the biocompatibility of nanospheres. Nature Nanotechnology (in submission), 2015.
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{Journal Article }
Tsai Y-T, Hu, W.J., Tang L. Three-dimensional quantification and visualization model for drug delivery in eyes. Nature Methods (in submission), 2015.
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{Journal Article }
Wu J, Ding Q, Dutta A, Wang Y, Huang Y, Weng H, Tang L, Hong Y. An injectable extracellular matrix derived hydrogel for meniscus repair and regeneration. Acta Biomaterials (in revison), 2015.
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{Journal Article }
Cao J, Chen D, Huang S, Deng D, Tang L, Gu Y. Cyclic RGD-modified near-infrared light triggered micelles for tumor targeting and therapy. (in submission), 2015.
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{Journal Article }
Phipps MC, Huang YH, Yamaguchi R, Kamiya N, Tang L, Kim HKW. In vivo monitoring of activated macrophages and neutrophils in response to ischemic osteonecrosis in a mouse model. (in submission), 2015.
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{Journal Article }
Kang M, Tang L, Gao JX. Computational modeling of foreign body responses on biomaterial-implanted mice. IEEE Transactions on Information Technology in Biomedicine (in submission), 2015.
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{Peer Reviewed }
Nair A, Baker D, Tang L. Biological and chemical influence on immune and regenerative responses to biomaterial implants. Woodhead publisher (book chapter) (in press), 2013.
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{Peer Reviewed }
Wadajkar AS, Santimano S, Tang L, Nguyen KT. Magnetic-based multi-layer microparticles for endothelial progenitor cell isolation, enrichment, and detachment. Biomaterials 35:654-663, 2014.
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{Peer Reviewed }
Tsai Y-T,* Zhou J,* Weng H, Tang E. N., Baker D., Tang L. Optical imaging of fibrin deposition to elucidate mast cell participation on foreign body reactions. Biomaterials 35: 2089-96, 2014.
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{Peer Reviewed }
Pujari S, Hoess A, Shen J, Thormann A, Tang L, Karlsson-Ott M. Effects of nanoporous alumina on inflammatory cell responses. Journal of Biomedical Materials Research: Part A (in press), 2014.
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{Peer Reviewed }
Xie Z, Zhang, Liu L, Weng H, Mason RP, Tang L, Nguyen KT, Hsieh JT, Yang J. Development of intrinsically photoluminescent and photostable polylactones. Advanced Materials (in press), 2014.
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{Peer Reviewed }
Shen J, Nair A, Saxena R, Zhang CC, Borrelli J, Tang L. Tissue engineering bone using autologous progenitor cells in the peritoneum. PLOS ONE DOI: 10.1371/journal.pone. 0093514, 2014.
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{Journal Article }
Su L-C, Xu H, Tran RT, Tsai Y-T, Tang L, Banerjee S, Yang J, Nguyen KT. In situ re-endothelialization via multifunctional nano-scaffolds. ACS Nano 8(10): 10826-36, 2014.
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{Journal Article }
Baker DW, Zhou J, Tsai Y-T, Patty K, Weng H, Tang EN, Nair A, Hu W-J, Tang L. Development of optical probes for in vivo imaging of polarized macrophage responses. Acta Biomaterialia 10(7): 2945-55, 2014.
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{Journal Article }
Baker DW, Tsai Y-T, Weng H, Tang L. Alternative strategies to manipulate fibrocyte involvement in the fibrotic tissue responses: pharmacokinetic inhibition and the feasibility of directed-adipogenic differentiation. Acta Biomaterialia 10:3108-3116, 2014.
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{Peer Reviewed }
Xie Z, Paras CB, Weng H, Punnakitikashem P, Su LC, Vu K, Tang L, Yang J, Nguyen KT. Dual growth factor releasing multi-functional nanofibers for wound healing. Acta Biomaterialia 9(12): 9351-9359, 2013.
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{Peer Reviewed }
Zhang Y, Tran RT, Qattan I, Tsai Y-T, Tsai Y-T, Tang L, Liu C, Yang J. Fluorescence imaging enabled urethane-doped citrate-based biodegradable elastomers. Biomaterials 34:4048-4056, 2013.
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{Peer Reviewed }
Sohaebuddin SK, Tang L. A simple method to visualize and assess the integrity of lysosomal membrane in mammalian cells using a fluorescent dye. Method in Molecular Biology 991:25-31, 2013. doi: 10.1007/978-1-62703-336-7_3.
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{Peer Reviewed }
Sohaebuddin SK, Tang L. A simple method to visualize and assess the integrity of lysosomal membrane in mammalian cells using a fluorescent dye. Method in Molecular Biology 991:25-31, 2013. doi: 10.1007/978-1-62703-336-7_3.
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{Peer Reviewed }
Yang J, Su J, Perkins L, Ibaguimov A, Tang L. A computational model of fibroblasts and macrophages spatial/temporal dynamics in foreign body reactions. Journal of Immunological Methods 397 (1-2): 37-46, 2013.
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{Peer Reviewed }
Zhou J, Hao G, Weng H, Tsai Y-T, Baker DW, Sun X, Tang L. In vivo evaluation of implant-associated inflammation by macrophage specific probe with Positron Emission Tomography (PET) imaging. Bioorganic & Medicinal Chemistry Letters, 23: 2044-2047, 2013 [NIHMS#445371].
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{Peer Reviewed }
Tsai Y-T,* Zhou J,* Weng H, Tang L, Hu W-J. Real-time noninvasive in vivo inflammatory responses by pH ratiomatric fluorescence imaging probe. Advanced Healthcare Materials, DOI: 10.1002/adhm.201200365, 2013. *Both authors contributed equally to this work.
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{Peer Reviewed }
Cao J, Hung S, Chen Y, Deng D, Li X, Qian Z, Tang L, Gu YQ. Novel Near-Infrared light-triggered micelles for fast controlled drug release in deep tissue. Biomaterials 34:6272-6283, 2013.
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Ko C-K, Wu L, Nair AM, Tsai Y-T, Lin VK, Tang L. Development of cancer traps for eliminating metastatic melanoma cells. CPRIT conference, 2012{Conference Proceeding }
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Zhou J, Tsai Y-T, Weng H, Tang EN, Baker D, Tang L. Development of nanoprobes for imaging foreign body reactions. European Cells and Materials 23 Suppl 5, page 3 2012{Conference Proceeding }
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Zhou J, Tsai Y-T, Weng H, Nair A, Tang L. Novel near-infrared probe for in vivo detection of biomaterial-mediated neutrophil responses. 9th World Biomaterials Congress, 2012{Conference Proceeding }
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Tsai Y-T, Zhou J, Weng H, Tang L. Real-time noninvasive in vivo imaging of foreign body reactions using pH ratiometric fluorescence probes. 9th World Biomaterials Congress, 2012{Conference Proceeding }
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Montoya I., Zhou J, Tang L, Word R.A. Development of thermosensitive nanoparticles hydrogel for protein delivery in connective tissues of the pelvic floor. 2012 33rd Annual American Urogynecologic Society Conference, 2012{Conference Proceeding }
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Zhou J, Tsai, Y-T, Weng H, Tang EN, Baker D, Tang L. Development of nanoprobes for imaging foreign body reactions. 5th Annual Meeting of the Scandinavian Society of Biomaterials, 2012.{Conference Proceeding }
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Nguyen KT, Xie Z, Su L-C, Xu H, Kona S, Tang L, Dong J-F, Barnerjee S, Yang J. Biomimetic multi-functional nanoparticles for treatment of cardiovascular diseases. BMES 2012 conference, 2012{Conference Proceeding }
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Nair AM, Shen J, Tsai Y-T, Sun X, Saxena R, Tang L. Erythropoietin enhances osteogenic differentiation of autologous stem cells in critical size defects. BMES 2012 conference (accepted), 2012{Conference Proceeding }
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Tang L, Hu W-J. Biochips for detecting polymicrobial infection (Editorial). Biochip & Tissue Chips, 2.3, 2012. http://dx.doi.org/10.4172/2153-0777.1000e115{Journal Article }
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Cai T, Hu P, Sun M, Zhou J, Tsai Y-T, Baker DW, Tang L. Novel thermogelling dispersions of polymer nanoparticles for controlled protein release. Nanomedicine (in press), 2012{Journal Article }
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Cao J, Zhu HY, Deng DW, Xue B, Tang L, Mahounga D, Qian Z, Gu YQ. In vivo NIR imaging with PbS Quantum Dots entrapped in biodegradable micelles. Journal of Biomedical Materials Research: Part A 100A (4): 958-68, 2012{Journal Article }
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Wadajkar AS, Bhavsar Z, Ko CY, Koppolu B, Cui W, Tang L, Nguyen KT. Multifunctional nanoparticles for melanoma-targeted drug delivery. Acta Biomaterialia 8:2996-3004, 2012.{Journal Article }
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Mehdizadeh M, Weng H, Tang L, Yang J. Citrate-enabled one-step syntheses of mussel-inspired biodegradable strong adhesive for sutureless wound closing. Biomaterials 33(32): 7972-7983, 2012{Journal Article }
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Ibragimov AI, Su J, Perkins L, Tang L. Stability analysis of a model for foreign body fibrotic reactions. Computational and Mathematical Models in Medicine, Article ID 809864, 11 pages, doi:10.1155/2012/809864, 2012{Journal Article }
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Zhou J,* Tsai Y-T,* Weng H, Tang L. Noninvasive assessment of localized inflammatory responses. Free Radical Biology & Medicine 52: 218-226, 2012.{Journal Article }
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Ko C-Y,* Wu L,* Nair A, Tsai YT, Lin VK, Tang L. Use of chemokine releasing tissue engineering scaffolds in studying inflammatory responses-mediated cancer metastasis. Biomaterials 33(3):876-885, 2012.{Journal Article }
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{Peer Reviewed }
Prieto-Langarica A, Kojouharov H, Tang L. Construction one-dimensional continuous models from two-dimensional discrete models of medical implants. Biomath 2012 (1): A001 (1-5).
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Zhou J, Tsai Y, Weng H, Baker D, Tang L. New nanoprobes for assessing foreign body reactions in vivo. 27th Southern Biomedical Engineering Conference, OP:T5, SE 5.5, 2011{Conference Proceeding }
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Su, J, Yang J, Perkins L, Todorov M, Tang L. Predictive tools for foreign body fibrotic reactions using 2-Dimensional computational model. 27th Southern Biomedical Engineering Conference, OP:T1, SE 2.4, 2011{Conference Proceeding }
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Ferraz N, Hoess A, Thormann A, Heilmann A, Shen J, Tang L, Ott MK. Role of alumina nanoporosity in acute cell responses. European Cells and Materials. 21: suppl. 1, 16, 2011{Conference Proceeding }
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Zhou J, Tsai Y-T, Weng H, Tang L. Noninvasive monitoring of implant-mediated inflammatory responses by detecting reactive oxygen species in vivo. Transaction of the Society for Biomaterials, 175, 2011.{Conference Proceeding }
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Nair A, Shen J, Tsai Y-T, Tang L. Orchestrated stem cell-based regeneration (OSCeR) for bone tissue engineering, Transaction of the Society for Biomaterials, 896, 2011{Conference Proceeding }
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Nair A, Shen J, Tran RT, Guleserian K, Yang J, Tang L. Engineering vascular grafts via orchestrated autologous progenitor cell responses. 27th Southern Biomedical Engineering Conference, OP:T6, SE 1.5, 2011{Conference Proceeding }
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Su L, Tran R, Tsai Y, Tang L, Yang J, Nguyen KT. In situ re-endothelialization via multifunctional urethane-doped polyester (UPE) nanoscaffold. 27th Southern Biomedical Engineering Conference, OP:T6, SE 3.2, 2011{Conference Proceeding }
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Baker DW, Liu X, Weng H, Luo C, Tang L. Fibroblast/fibrocyte: surface interaction dictates tissue reactions to micropillar implants. 27th Southern Biomedical Engineering Conference, OP:T6, SE 4.2, 2011{Conference Proceeding }
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Zou L, Nair A, Weng H, Tsai YT, Hu Z, Tang L. Intraocular pressure changes: The critical determinant of the biocompatibility of intravitreous implants. PLoS ONE 6(12): e28720. doi:10.1371/journal.pone.0028720, 2011{Journal Article }
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Tang L. In vivo diagnosis: a future direction for biochip technology (Editorial). Biochip & Tissue ChipsS1:002 doi:10.4172/2153-0777.S1-002, 2011{Journal Article }
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Su J, Gonzales HP, Todorov M, Kojouharov H, Tang L. A mathematical model for implant-associated fibrotic tissue reactions in 2D. International Journal of Computer Mathematics, 88(3): 601-33, 2011.{Journal Article }
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Su J, Todorov M, Gonzales HP, Perkins L, Kojouharov H, Weng H, Tang L. A predictive tool for foreign body fibrotic reactions using 2-dimensional computational model. Open Access Bioinformatics 3:19-35, 2011.{Journal Article }
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Nair A, Lotfi P, Shen J, Ko CY, Zhang CC, Tang L. Biomaterial implants mediated autologous stem cell recruitment in mice. Acta Biomaterialia 7: 3887-3895, 2011.{Journal Article }
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Baker D, Liu X, Weng H, Luo C, Tang L. Fibroblast/fibrocyte:surface interaction dictates tissue reactions to micropillar implants. Biomacromolecules 12(4):997-1005, 2011{Journal Article }
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Ferraz N, Hoess A, Thormann A, Heilmann A, Shen, J, Tang L, Ott MK. Influence of alumina nanoporosity on biomaterial-mediated acute inflammatory responses. Journal of Nanotechnology and Nanoscience 11(8):6698-6704, 2011.{Journal Article }
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Thevenot PT,* Baker D,* Weng H, Tang L. The pivotal role of fibrocytes and mast cells in mediating fibrotic responses to biomaterials. Biomaterials 32:8394-8403, 2011.{Journal Article }
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Shen J, Tsai Y-T, DiMarco N, Long MA, Sun XK, Tang L. Delayed osteoporosis in old mice by transplantation of mesenchymal stem cells from young donors. Scientific Report 1,67; DOI:10.1038/srep00067, 2011{Journal Article }
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Zhou J,* Tsai Y-T,* Weng H, Baker D, Tang L. Real time monitoring of biomaterial-mediated inflammatory responses by targeting activated macrophages in vivo with folate receptor-targeting NIR nanoprobe. Biomaterials 32:9383-9390, 2011{Journal Article }
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Sharma V, Patel N, Shen J, Tang L, Alexandrakis G, Liu H. A dual-modality optical biopsy approach for in vivo detection of prostate cancer in rat model. Journal of Innovative Optical Health Sciences 4(3): 269-77, 2011.{Journal Article }
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{Peer Reviewed }
Hoess A, Ferraz N, Thormann A, Heilman A, Shen J, Tang L, Ott K. In vivo acute inflammatory responses to nanoporous alumina. 24th European Conference on Biomaterials, Dublin, September 4-8, 2011. http://urn.kb.se/resolve?urn=urn:nbn: se:uu:diva-163817.
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Wadajkar A, Rajan P, Bhavsar Z, Koppolu B, Zhang Y, Cui W, Tang L, Yang J, Nguyen K. Theranostic nanoparticles for cancer diagnosis and treatment. BMES 2010 conference, 7B-7-86, Austin, Texas.{Conference Proceeding }
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Nair A, Shen J, Sun M-W, Zhang A, Tang L. Biomaterial implant recruits and differentiates autologous stem cells. BMES 2010 conference, 8A-19-247, Austin, Texas.{Conference Proceeding }
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Tsai Y-T, Hu W-J, Tang L. Three-dimensional quantification and visualization model for drug delivery in eyes. BMES 2010 conference, 8B-2-18, Austin, Texas{Conference Proceeding }
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Ko C-Y, Nair A, Tsai Y-T, Zhou J, Tang L. Development of cancer traps for eliminating metastatic cancer cells in vivo. BMES 2010 conference, 9A-6-80, Austin, Texas{Conference Proceeding }
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Aphale N, Xu H, Gyawali D, Wadajkar A, Tang L, Yang J, Nguyen K. In situ composite hydrogel system for treatment of complex wounds. BMES 2010 conference, 7B-7-92, Austin, Texas{Conference Proceeding }
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Zhou J, Tsai Y-T, Weng H, Tang L. Novel near-infrared fluorescence (NIR) nanoprobes for in vivo imaging of inflammatory diseases. BMES 2010 conference, OP-9-1-16-B, Austin, Texas{Conference Proceeding }
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Nair A, Thevenot P, Dey J, Sun M-W, Yang J, Tang L. Novel polymeric scaffold using protein microbubbles as porogen and growth factor carriers. Tissue Engineering 16:23-32, 2010 [PMCID: PMC2818248].{Journal Article }
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Tran, R.; Thevenot, P.; Gyawali, D.; Chiao, J. C.; Tang, L.; Yang, J. Development of a novel biodegradable elastomer featuring a dual crosslinking mechanism for soft tissue engineering. Soft Matter 2010, 6, 2449-2461.{Journal Article }
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Thevenot, P.; Nair, A.; Shen, J.; Lotfi, P.; Ko, C. Y.; Tang, L. The effect of incorporating of SDF-1? into PLGA scaffolds on stem cell recruitment and the inflammatory responses. Biomaterials 2010, 31 (14), 3997-4008.{Journal Article }
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Sohaebuddin, S.; Thevenot, P.; Baker, D.; Eaton, J. W.; Tang, L. Nanomaterial cytotoxicity is composition, size, and cell type dependent. Particle and Fibre Toxicology 2010, 7, 22.{Journal Article }
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Gyawali, D.; Tran, R. T.; Guleserian, K. J.; Tang, L.; Yang, J. Citric acid-derived photocrosslinked biodegradable elastomers. Journal of Biomaterials Science 2010, 21, 1761-1781.{Journal Article }
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Tran, R. T.; Thevenot, P.; Zhang, Y.; Gyawali, D.; Tang, L.; Yang, J. Scaffold sheet design strategy for soft tissue engineering. Materials 2010, 3, 1375-1389.{Journal Article }
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Yang J, Gautam S, Liu L, Zhang Y, Dey J, Chen W, Mason RP, Tang L, Zhang C, Zheng J, Guleserian KJ. Development of novel aliphatic biodegradable fluorescent polymers for tissue engineering. The 27th Scientific Conference of the Society for Physical Regulation in Biology and Medicine (SPRBM), Oahu, Hawaii, Jan. 6-9, 2009{Conference Proceeding }
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Su J, Gonzales HP, Todorov M, Kojouharov H, Tang L. A mathematical model for foreign body reactions, preliminary report, in 105st AMS meeting, Baylor University, Waco, Texas, Oct 16-18, 2009, program, by American Mathematical Society, page 61{Conference Proceeding }
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Lin Z-J, Alexandrakis G, Patel NL, Shen J, Tang L, and Liu H. "Time-gated optical imaging to detect positive prostate cancer margins," in SPIE Photonics West (San Jose, CA, 2009), pp. 716119-1-9{Conference Proceeding }
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Lotfi P, Koshy A, Shen J, Tang L. Biomaterial-mediated recruitment of stem and progenitor cells. Transaction of the Society for Biomaterials, 145, 2009{Conference Proceeding }
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Kona S, Wavhal D, Timmons R, Tang L, Nguyen KT. In vitro evaluation of plasma surface-modified PLGA nanoparticles. Transaction of BMES, 2009{Conference Proceeding }
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Vadla A, Kona S, Wavhal D, Timmons R, Tang L, Nguyen KT. Surface functionalized biodegradable nanoparticles in cancer cells. Transaction of BMES, 2009{Conference Proceeding }
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Tang L, Tsai Y-T, Hu, W. Three-dimensional model for quantifying nanoparticle drug delivery in eyes. Transaction of the Annual Meeting of the Association for Research in Vision and Ophthalmology 5963/A586, 2009{Conference Proceeding }
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Ko C-Y, Wu L, Tang L. Melanoma cell recruitment induced by biomaterial-mediated inflammation involves in CCR7/CCL21 lymphatic pathway. 12th SCBA International Symposium 2009{Conference Proceeding }
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Zhang Y, Tang L, Yang J. Novel biodegradable aliphatic photoluminescent polymers. BMES Annual Fall Meeting, Pittsburgh, PA. Oct. 7-10, 2009{Conference Proceeding }
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Tran RT, Gyawali D, Thevenot P, Tang L, Yang J. A Biodegradable Elastomer Featuring a Dual Crosslinking Mechanism. ASAIO's 55th Annual Conference for The American Society for Artificial Organs, 2009{Conference Proceeding }
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Yang J, Zhang Y, Gautam S, Liu L, Mason R, Tang L. Novel Biodegradable Fluorescent Polymers for Biomedical Applications. The 4th WACBE World Congress on Bioengineering, Hong Kong, China, July 26-29, 2009{Conference Proceeding }
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Zhang Y, Gautam S, Liu L, Dey J, Tran RT, Gyawali D, Chen W, Mason RP, Tang L, Zheng J, Guleserian KJ, Yang J. Biodegradable photoluminescent polymeric biomaterials. 2009 UT Metroplex day, Arlington, Texas, March 6, 2009{Conference Proceeding }
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Tran T, Gyawali D, Thevenot P, Tang L, Yang J. A Biodegradable Elastomer Featuring a Dual Crosslinking Mechanism. ASAIO's 55th Annual Conference for the American Society for Artificial Organs (2009 ASAIO-IFAO), Dallas, Texas, May 28-30, 2009{Conference Proceeding }
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Hansen RH III, Shen J, Tang L. Localized recruitment of multipotent mesenchymal stem cells by biomaterial implants. Transaction of the Society for Biomaterials, 45, 2009{Conference Proceeding }
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Wu L, Ko C-Y, Tang L. Foreign body reactions-induced cancer metastasis. Transaction of the Society for Biomaterials, 52, 2009.{Conference Proceeding }
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Nair A, Yang J, Tang L. Novel porous scaffold for releasing bioactive molecules. Transaction of the Society for Biomaterials, 58, 2009{Conference Proceeding }
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Yang, J.; Gautam, S.; Zhang, Y.; Liu, L.; Dey, J.; Chen, W.; Mason, R. P.; Tang, L. Development of non-phenyl containing biodegradable photoluminescent polymers. Proceeding of National Academy of Science 2009, 106 (25), 10086-10091.{Journal Article }
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Nguyen, K.; Shukla, K. P.; Moctezuma, M.; Braden, A. R. C.; Zhou, J.; Hu, Z.; Tang, L. In vitro studies of the cellular uptake of hydrogel nano- and micro- particles by phagocytes, vascular endothelial and smooth muscle cells. Journal of Biomedical Materials Research 2009, 88 (4), 1022-30.{Journal Article }
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Tang L, Wu L, Ong M, Howe WE, Lin VK. Human lens epithelial cells possess stem cell like property. Transaction of the Annual Meeting of the Association for Research in Vision and Ophthalmology, D849, 2008{Conference Proceeding }
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Yang J, Tang L, Nguyen K, Chiao J-C. Novel biodegradable elastomers and scaffold-sheet tissue engineering. Transaction of 16th International Conference on Mechanics in Medicine and Biology. Pittsburgh, PA, 23th-25th July, 2008{Conference Proceeding }
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Yang J, Dey J, Thevenot P, Tang L, Nguyen KT. Novel biodegradable elastic polymers and scaffold-sheet tissue engineering strategy. Society for Biomaterials Translational Research Symposium. Atlanta, GA, September 11-13, 2008{Conference Proceeding }
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Thevenot PT, Javed A, Lotfi P, Antich P, Tang L. In vivo SDF-1α (CXCL12) mediated MSC recruitment to tissue engineering scaffold. TERMIS NA 2008, 505, 2008.{Conference Proceeding }
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Thevenot PT, Nair A, Sohaebuddin S, Tang L. Scaffold treatment with SDF-1α (CXCL12) diminishes the immune response. TERMIS NA-2008, 502, 2008.{Conference Proceeding }
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Gautam S, Liu L, Zhang Y, Dey J, Chen W, Mason RP, Tang L, Zhang C, Zheng J, Guleserian KJ, Yang J. Aliphatic biodegradable photoluminescent polymers. 2008 Cancer Imaging Program Symposium, Dallas, TX, November 13th-14th, 2008.{Conference Proceeding }
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Mathew J, Kache V, Liu C, Tang L, Yang J. Nano-featured highly interconnective macroporous elastic scaffolds for cardiovascular tissue engineering. UT Metroplex Day, Dallas, 2008{Conference Proceeding }
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Thevenot, P., Sohaebuddin, S., Poudyal, N., Liu, J. P., & Tang, L. (2008). Magnetic nanoparticles to enhance cell seeding and distribution in tissue engineering scaffolds. In IEEE Proceeding of Conference on Nanotechnology. IEEE Proceeding of Conference on Nanotechnology: 646-649, 2008.{Conference Proceeding }
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Su, J., Gonzales, H. P., & Tang, L. (2008). Modeling of foreign body reactions to neural implants. In Rubin Wang, Fanji Gu, Enhua Shen. (Eds.), Advances in Cognitive Neurodynamics ICCN 2007: Proceeding of the International Conference on Cognitive Neurodynamic (pp. 879-882). Spring Science+ Business Media BV.{Conference Proceeding }
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Xue, J., Gao, J., & Tang, L. (2008). Phagocyte transmigration modeling using system dynamic controls. Paper presented at IEEE Proceedings of International Symposium on Bioinformatics & Bioengineering (BIBE), IEEE Proceedings of International Symposium on Bioinformatics & Bioengineering.{Conference Paper }
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Nair, A., Shen, J., Thevenot, P., Cai, T., Hu, Z., & Tang, L. (2008). Novel quantum dots for enhanced tumor imaging. IEEE Proceeding of Conference on Nanotechnology: 650-653, 2008.{Conference Paper }
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{Peer Reviewed }
Nair A, Shen J, Thevenot P, Cai T, Hu Z, Tang L. Novel quantum dots for enhanced tumor imaging. IEEE Proceeding of Conference on Nanotechnology: 650-653, 2008 .
Zhang S, Zhou J, Hu Z, Nair A, Tang L. Nanoparticles for uveal melanoma treatment. IEEE Proceeding of Conference on Nanotechnology: 822-825, 2008 .
Thevenot P, Sohaebuddin S, Poudyal N, Liu JP, Tang L. Magnetic nanoparticles to enhance cell seeding and distribution in tissue engineering scaffolds. IEEE Proceeding of Conference on Nanotechnology: 646-649, 2008 .
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Zhang, S.; Zhou, J.; Hu, Z.; Nair, A.; Tang, L. Nanoparticles for uveal melanoma treatment. IEEE Proceeding of Conference on Nanotechnology 2008, 822-825.{Journal Article }
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Nair, A.; Shen, J.; Thevenot, P.; Zou, L.; Cai, T.; Hu, Z.; Tang, L. Enhanced intratumoral uptake of quantum dots concealed within hydrogel nanoparticles. Nanotechnology 2008, 19, 485102.{Journal Article }
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Thevenot, P.; Cho, J.; Timmons, R. B.; Tang, L. Surface chemistry influence cancer killing effect of TiO2 nanoparticles. Nanomedicine 2008, 4, 226-236.{Journal Article }
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Nair, A.; Zou, L.; Bhattacharyya, D.; Timmons, R. B.; Tang, L. Species and density of implant surface chemistry affect the extent of foreign body reactions. Langmuir 2008, 24 (5), 2015-2024.{Journal Article }
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Dey, J.; Xu, H.; Shen, J.; Thevenot, P.; Gondi, S. R.; Nguyen, K. T.; Sumerlin, B. S.; Tang, L.; Yang, J. Development of biodegradable crosslinked urethane-doped polyester elastomers. Biomaterials 2008, 29, 4637-4649.{Journal Article }
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Thevenot, P.; Hu, W.; Tang, L. Surface chemistry influence implant biocompatibility. Current Topics in Medical Chemistry 2008, 8 (4), 270-280.{Journal Article }
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Zhou, J.; Wang, G.; Zou, L.; Tang, L.; Marquez, M.; Hu, Z. Viscoelastic behavior and in vivo release of microgel dispersions with inverse thermo-reversible gelation. Biomicromolecules 2008, 9 (1), 142-148.{Journal Article }
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Kamath, S.; Bhattacharyya, D.; Padukudru, C.; Timmons, R. B.; Tang, L. Surface chemistry influence implant mediated host tissue response. Journal of Biomedical Materials Research 2008, 86A (3), 617-626.{Journal Article }
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Nair, A.; Thevenot, P.; Hu, W.; Tang, L. Nanotechnology in the treatment and detection of intraocular cancers. Journal of Biomedical Nanotechnology 2008, 4, 410-418.{Journal Article }
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Bhattacharyya D, Susut S, Cho J, Tang L, Timmons RB. Plasma generated polymer films for drug delivery applications. Transactions of the Drug Delivery Society, Invited speaker, July, 2007.{Conference Proceeding }
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Mathew J, Kache V, Liu C, Tang L, Yang J. Nano-featured highly interconnective macroporous elastic scaffolds for cardiovascular tissue engineering. IEEE Proceeding of Engineering in Medicine and Biology Workshop, 43-46, 2007.{Conference Proceeding }
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Thevenot PT, Tang L. Characterization of cell distribution and infiltration into PLGA salt leached scaffolds. IEEE Proceeding of Engineering in Medicine and Biology Workshop, 39-42, 2007.{Conference Proceeding }
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Nair A, Yang J, Tang L. A novel preparation of polymeric scaffolds using protein microbubbles as porogen. IEEE Proceeding of Engineering in Medicine and Biology Workshop, 31-34, 2007.{Conference Proceeding }
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Xue J., Gao J., Tang L, Mathematical modeling of phagocyte chemotaxis and adherence to biomaterial implants. In . IEEE Proceedings of International Conference on Bioinformatics & Biomedicine (BIBM): 302-307, 2007.{Conference Proceeding }
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Xue J, Gao J, Tang L. Phagocyte transmigration modeling using system dynamic controls. IEEE Proceedings of International Symposium on Bioinformatics & Bioengineering (BIBE): 480-485, 2007{Conference Paper }
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Xue J, Gao J, Tang L. Mathematical modeling of phagocyte chemotaxis and adherence to biomaterial implants. IEEE Proceedings of International Conference on Bioinformatics & Biomedicine (BIBM): 302-307, 2007.{Conference Paper }
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Thevenot, P. T. & Tang, L. (2007). Characterization of cell distribution and infiltration into PLGA salt leached scaffolds. IEEE Proceeding of Engineering in Medicine and Biology Workshop, 39-42, 2007.{Conference Paper }
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Nair, A., Yang, J., & Tang, L. (2007). A novel preparation of polymeric scaffolds using protein microbubbles as porogen. Paper presented at IEEE Proceeding of Engineering in Medicine and Biology Workshop, IEEE Proceeding of Engineering in Medicine and Biology Workshop, 31-34, 2007.{Conference Paper }
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Mathew, J., Kache, V., Liu, C., Tang, L., & Yang, J. (2007). Nano-featured highly interconnective macroporous elastic scaffolds for cardiovascular tissue engineering. Paper presented at IEEE Proceeding of Engineering in Medicine and Biology Workshop, IEEE Proceeding of Engineering in Medicine and Biology Workshop,.{Conference Paper }
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{Peer Reviewed }
Xue J, Gao J, Tang L. Phagocyte transmigration modeling using system dynamic controls. IEEE Proceedings of International Symposium on Bioinformatics & Bioengineering (BIBE): 480-485, 2007.
2)Mathew J, Kache V, Liu C, Tang L, Yang J. Nano-featured highly interconnective macroporous elastic scaffolds for cardiovascular tissue engineering. IEEE Proceeding of Engineering in Medicine and Biology Workshop, 43-46, 2007.
Nair A, Yang J, Tang L. A novel preparation of polymeric scaffolds using protein microbubbles as porogen. IEEE Proceeding of Engineering in Medicine and Biology Workshop, 31-34, 2007.
Thevenot PT, Tang L. Characterization of cell distribution and infiltration into PLGA salt leached scaffolds. IEEE Proceeding of Engineering in Medicine and Biology Workshop, 39-42, 2007.
Xue J, Gao J, Tang L. Mathematical modeling of phagocyte chemotaxis and adherence to biomaterial implants. IEEE Proceedings of International Conference on Bioinformatics & Biomedicine (BIBM): 302-307, 2007.
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Jiang W-W, Su S-H, Eberhart RC, Tang L. Phagocyte responses to degradable polymers. Journal of Biomedical Materials Research 82(2):492-497, 2007{Journal Article }
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Bhattacharyya, D.; Pillai, K.; Chyan, O. M. R.; Tang, L.; Timmons, R. B. A new class of thin film hydrogels produced by plasma polymerization. Chemistry of Materials 2007, 19 (9), 2222-2228.{Journal Article }
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Nguyen, K. T.; Shukla, K. P.; Moctezuma, M.; Tang, L. Cellular and molecular responses of smooth muscle cells to surfaces  nano-topography. Journal of Nanoscience and Nanotechnology, 2007, 7, 2823-2832.{Journal Article }
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Andersson, M.; Hedlund, J.; Berglin, M.; Elwing, H.; Tang, L. Molecular mobility of polymeric implants and acute inflammatory responses: An experimental study in mice. Journal of Materials Science: Materials in Medicine 2007, 18 (2), 283-286.{Journal Article }
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W-W, J.; S-H, S.; Eberhart, R. C.; Tang, L. Phagocyte responses to poly L-lactic acid. Journal of Biomedical Materials Research 2007, 82 (2), 492-497.{Journal Article }
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Bhattacharyya, D.; Pillai, K.; Tang, L.; Timmons, R. B. Immobilization of biomolecules on pulsed plasma polymerized poly(vinylacetic acid) thin films. PMSE Preprints 2007, 96, 340-341.{Journal Article }
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Zdolsek, J.; Eaton, J. W.; Tang, L. Histamine release and fibrinogen adsorption mediate acute inflammatory responses to biomaterial implants in human. Journal of Translational Research 2007, 5, 31.{Journal Article }
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Kriparamanan, R.; Aswath, P.; Zhou, A.; Tang, L.; Nguyen, K. T. Nanotography:cellular responses to nanostructured materials. Journal of Nanoscience and Nanotechnology 2006, 6 (7), 1905-1919.{Journal Article }
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Jr, A. W. P.; Haydon, M. S.; Jr, R. J.; Trott, S.; Marques, M.; Feliciano, M.; Jr, R. J. B.; Tang, L.; Brown, S. A. A rabbit model for capsule contracture: development and clinical implications. Plastic and Reconstructive Surgery 2006, 117, 1214-1219.{Journal Article }
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Kalsson, M.; Tang, L. Surface morphology and adsorbed proteins affect phagocyte responses to nano-porous alumina. Journal of Material Science: Materials in Medicine 2006, 17 (1), 1101-1111.{Journal Article }
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Ramanan, R. M. K.; Chellamuthu, P.; Tang, L.; Nguyen, K. T. Development of a thermoresponsive composite hydrogel for drug delivery application. Biotechnology Progress 2006, 22 (1), 118-125.{Journal Article }
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Hu, Z. B.; Xia, X. H.; Marques, M.; Weng, H.; Tang, L. Hydrogel nanoparticles dispersions and their tissue response. Macromolecular Symposia 2005, 227, 275-284.{Journal Article }
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Tang, L.; Hu, W. J. Molecular determents of biocompatibility. Expert Review of Medical Devices 2005, 2 (4), 493-500.{Journal Article }
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S-H, S.; Nguyen, K. T.; Brouse, C. F.; Greukucg, P. E.; Tang, L.; Eberhart, R. C. Curcumin impregnation improves the mechanical properties and reduces the inflammatory responses associated with poly(L-lactic acid) fibers. Journal of Biomaterials Science Polymer Edition 2005, 16 (3), 353-370.{Journal Article }
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Nguyen KT, Su S-H, Shaikh N, Eberhart RC, Tang L. Molecular responses of cultured vascular smooth muscle cells and activated phagocytes to curcumin-eluting bioresorbable stent materials. Biomaterials, 25:5333-5346, 2004{Journal Article }
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Nguyen KT, Shaikh N, Wawro D, Schwade ND, Eberhart RC, Tang L. Molecular responses of cultured vascular smooth muscle cells to paclitaxel-eluting bioresorbable stent materials. Journal of Biomedical Materials Research, 69A:513-524, 2004.{Journal Article }
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Busuttil SJ, Ploplis VA, Castellino FJ, Tang L, Eaton JW, Plow EF. A central role for plasminogen in the inflammatory response to biomaterials. Journal of Thrombosis and Haemostasis, 2(10): 1798-1805, 2004.{Journal Article }
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Weng H, Zhou J, Tang L, Hu Z. Tissue responses to thermally responsive hydrogel nanoparticles. Journal of Biomaterials Science Polymer Edition, 15(9):1167-1180, 2004.{Journal Article }
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L. Tang, "Molecular Mechanism of Biomaterial-mediated Phagocyte Responses," Biomaterial Engineering and Devices: Human Applications, Volume 1. Fundamentals and Vascular and Carrier Applications. DL Wise, JD Gressser, DJ Trantolo, MV Cattaneeo, K-U Lewandr{Journal Article }
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L. Tang, Y. Wu and R. B. Timmons, "Biomaterial Surface Properties Affecting both Protein Adsorption and Host Tissue Responses," Journal of Biomedical Materials Research, Vol. 42, pp. 156-163, 1998.{Journal Article }
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L. Tang, T. A. Jennings and J. W. Eaton, "Mast Cells Mediate Acute Inflammatory Responses to Implanted Biomaterials," Proceedings of National Academy of Science, USA, Vol. 95, pp. 8841-8846, 1998.{Journal Article }
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L. Tang and J. W. Eaton, "Adsorbed Fibrinogen Mediates Acute Inflammatory Responses to Biomaterials," Journal of Experimental Medicine, Vol. 178, pp. 2147-2156, 1993.{Journal Article }
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{Peer Reviewed }
Tang L, Lucas AH, Eaton JW. Inflammatory responses to polyethylene terephthalate: Role of surface-adsorbed IgG. Journal of Laboratory and Clinical Medicine, 122:292-300, 1993.
Tang L, Eaton JW. Adsorbed fibrinogen mediates acute inflammatory responses to biomaterials. Journal of Experimental Medicine, 178:2147-2156, 1993.
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Journal Article
Revised and Resubmitted
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Journal Article
2014
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Book Chapter
2013
Journal Article 2013
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Conference Proceeding
2012
Journal Article 2012
Book Chapter 2012
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Conference Proceeding
2011
Journal Article 2011
Conference Paper 2011
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Conference Proceeding
2010
Journal Article 2010
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Conference Proceeding
2009
Journal Article 2009
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Conference Proceeding
2008
Conference Paper 2008
Journal Article 2008
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Conference Proceeding
2007
Conference Paper 2007
Journal Article 2007
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Journal Article
2006
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Journal Article
2005
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Journal Article
2004
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Journal Article
2000
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Journal Article
1999
Book Chapter 1999
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Journal Article
1998
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Journal Article
1993
Presentations
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November 2014
“New directions on tissue engineering, inflammation imaging and cancer therapy”Visiting Professor Lecture, China Pharmaceutical University, Department of Biomedical Engineering, Nanjing, China.
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November 2014
"Development of an implantable device for trapping metastatic cancer cells”Visiting Professor Lecture, Nanjing University of Aeronautics and Astronautics, Department of Biomedical Engineering, Nanjing, China.
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October 2014
“Development of optical probes for imaging inflammation”Invited speaker, Center for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada.
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September 2014
“Development of imaging probes and microscaffolds for minimal invasive disease detection and tissue regeneration”Invited speaker,National Central University, Tao Yuan County, Taiwan.
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September 2014
“Novel approaches for inflammatory disease detection, drug delivery, and tissue regeneration”Invited speaker, Show Chwan Health Care System – Asian Institute of TeleSurgery, Changhua County, Taiwan.
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August 2014
“Development of optical probes for imaging inflammation"Invited Guest Speaker, hosted by the College of Life Science, Kaohsiung Medical University, Kaohsiung, Taiwan.
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August 2014
“Novel scaffold design for inducing tissue regeneration via autologous stem cells"Invited Speaker, 2014 International Conference of Stem Cells and Tissue Engineering hosted by Kaohsiung Medical University, Kaohsiung, Taiwan.
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August 2014
“Novel approach for inducing autologous stem cell-mediated bone"Keynote speaker,The 3rd International Symposium of Materials on Regenerative Medicine, Chang Gung University, Taoyuan County, Taiwan.
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August 2013
"Potential role of inflammatory cytokines and T lymphocytes on cancer cell metastasis and cancer trap development"University of Louisville, Molecular Targets group, Brown Cancer Center, Louisville, Kentucky
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May 2013
“Novel approaches for inducing bone regeneration and imaging inflammation”Guest speaker,Biomaterial Interest Group meeting, The University of Texas Southwestern Medical Center at Dallas, Texas.
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- Past
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2005, August 20, Presentation title: "The current status and future promise of adult stem cell therapies. ", Convention for Chinese Institute of Engineers (CIE/USA), Dallas, Texas.
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- Past
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2009, October 7, Presentation title: "Emerging trends of nanotechnology in biomedical research", University of Texas at Arlington, Physics Department Colloquium, Arlington, Texas.
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- Past
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2005, October 6, Presentation title: "Development of drug delivery nanoparticles.", Department of Cell Biology and Genetics, University of North Texas Health Science Center at Fort Worth, Fort Worth, Texas.
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- Past
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2000, January, Presentation title: "Molecular mechanisms of biomaterial-mediated tissue responses.", Children Hospital Oakland Research Institute, Oakland, California.
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- Past
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2005, November 1, Presentation title: "Stem cell therapy: promise and problems.", Master of Arts in interdisciplinary Science program, University of Texas at Arlington, Arlington, Texas.
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- Past
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2000, April, Presentation title: "Foreign body reaction and device-centered infection.", Center of Immunology and Microbiology, Albany Medical College, Albany, New York.
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- Past
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2005, December 9, Presentation title: "Molecular mechanisms of foreign body reactions.", UMKC-CRISP seminar, University of Missouri at Kansas City, Kansas City, Missouri.
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- Past
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2001, March 2, Presentation title: "Albumin-affinity coating for improving biocompatibility.", Department of Materials Science and Engineering, University of Texas at Arlington, Arlington, Texas
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- Past
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2006, February 2, Presentation title: "Development of tissue-targeted nanoparticles for treatment of eye diseases.", JSPS Symposium on Nanoscale Materials for optoelectronics and biotechnology at University of North Texas, Denton, Texas.
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- Past
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2001, December 10, Presentation title: "Inflammatory and fibrotic reactions to implanted biomaterials: mechanisms and implications.", Pathology Department, University of Linkoping, Linkoping, Sweden.
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- Past
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2006, April 10, Presentation title: "Nanoparticles for drug delivery.", BioNano meeting atUniversity of Texas at Dallas, Dallas, Texas.
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- Past
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2002, August 24, Presentation title: "Dog skin plasters and drug controlled deliver devices.", Convention for Chinese Institute of Engineers (CIE/USA), Dallas, TX.
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- Past
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2006, July 12, Presentation title: "Controlled drug delivery: promise and problems.", Mid-Cities Technical Club of Arlington monthly seminar, Arlington, Texas.
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- Past
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2003, July 21, Presentation title: "Biomaterial-mediated inflammation and device-centered infection: Is there a connection?", Gordon Research Conference, Biomaterials: Biocompatibility/Tissue Engineering. HoldernessSchool, Polymouth, New Ham
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- Past
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2006, September 7, Presentation title: "Inflammation and cancer cell metastasis: Is there any connection?", University of Louisville, Molecular Targets group, Brown Cancer Center, Louisville, Kentucky
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- Past
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2004, February 5, Presentation title: "Foreign body reactions and stem cell recruitment " Is there any connection?", University of Louisville, Brown CancerCenter, Louisville, Kentucky.
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- Past
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2006, December 13, Presentation title: "Mechanism-based approaches for altering fibrotic tissue responses to peritoneal implants", Boston Scientific In., Urology Division, Boston, Massachusetts.
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- Past
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2004, April 16, Presentation title: "UTA capabilities and facilities for industrial joint ventures.", Alcon Laboratories, Inc., Fort Worth, Texas.
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- Past
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2007, December 13, Presentation title: "Stem cells: aging: osteoporosis", University of Louisville, Molecular Targets group, Brown Cancer Center, Louisville, Kentucky.
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- Past
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2002, February 1, Presentation title: "Biocompatibility and sensibility of implantable sensor.", Automation and Robotics Research Institute, University of Texas at Arlington, Fort Worth, TX.
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- Past
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2005, May 27, Presentation title: "Engineered biomaterials for tissue engineering and stem cell therapies.", Department of Biology, National Changhua University of Education, Changhua, Taiwan.
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- Past
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2008, January 30, Presentation title: "Potential role of inflammation on cancer cell metastasis", University of North Texas Health Science Center, Institute for Cancer & Blood Disorder, Fort Worth, Texas.
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- Past
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2000, October, Presentation title: "Artificial Blood.", Biomedical Engineering program. University of Texas at Arlington, Arlington, Texas.
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- Past
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2008, February 20, Presentation title: "Biomaterial-mediated inflammation and device-centered infection: Is there a connection?", University of Texas Southwest Medical Center, Surgery Research Conference, Dallas, Texas.
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- Past
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2003, August 28, Presentation title: "Foreign body reactions - Natural responses to unnature materials. ", 2003 University of Washington Engineered Biomaterials (UWEB) Summer Scientific Symposium, Seattle, Washington.
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- Past
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2009, September 18, Presentation title: "Novel in situ stem cell tissue engineering "Turing old foes into new friends", University of Texas at Arlington and University of Texas Southwest Medical Center at Dallas, Bioengineering Videoconfere
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- Past
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2009, March 4, Presentation title: "Potential role of inflammatory cytokines and T lymphocytes on cancer cell metastasis", University of North Texas Health Science Center, Institute for Cancer Grand Round, Fort Worth, Texas.
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- Past
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2008, May 9, Presentation title: "Intraocular lens and cataract surgery", Northstar School, Arlington, Texas.
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- Past
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2008, April 9, Presentation title: "Hyaluronic acid nanoparticles for retinal drug delivery", Drug Delivery group meeting, Alcon Laboratories, Inc., Fort Worth, Texas.
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- Past
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2004, April 16, Presentation title" Novel inflammation-recruited pluripotent stem cells.", Texas Back Institute, Plano, Texas.
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- Past
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2003, May 27, Presentation title: "The molecular mechanism of foreign body reactions: The implications to sensor development.", Molecular Design of Chemical Systems (MODECS) meeting, Novo Nordisk, Hilleroed, Denmark.
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- Past
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2001, August 14, Presentation title: "Molecular mechanisms of inflammatory responses to peritoneal implants.", Infimed Therapeutics, Inc., Cambridge, Massachusetts.
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- Past
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2000, March, Presentation title: "Phagocyte: surface interaction.". Pittsburgh Conference. "In vivo sampling. Biocompatibility issues" section, New Orleans, Louisiana.
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- Past
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2004, May 11, Presentation title: "Novel peritoneal stem cells.", Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
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- Past
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May 21, Academic Lecture, Presentation title: "Nanotechnology fro drug delivery and in vivo imaging".
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- Past
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2012, October 8th, Presentation title: "Development of optical probes for imaging inflammation", Guest speaker, Chemistry & Biochemistry Society, The University of Texas at Arlington, Arlington, Texas.
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- Past
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May 28, Academic Lecture, Presentation title: "Becoming a biomedical engineer ��" a less known career option for biologist".
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- Past
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2010, April 30, Laboratory tour and Presentation title: "New developments in tissue Engineering and Regenerative Medicine", Capital Staffers Visit, University of Texas at Arlington, Arlington, Texas.
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- Past
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May 31, Discussion of Techniques, Presentation title: "Fabrication of controlled release carriers".
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- Past
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June 2, Presentation title: "Stem cell culture and tissue engineering", Faculty of Biomedical Science and Environment Biology.
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- Past
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June 7, Discussion of Techniques, Presentation title: "In vivo imaging".
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- Past
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June 4, Presentation title: "Biomaterial and tissue engineering research in comtemporary medicine", Faculty of Biomedical Science and Environment Biology.
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- Past
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June 8, Academic Lecture, Presentation title: "How safe are medical devices?".
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- Past
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2010, October 29, Presentation title: "Development of pH sensitive probes for real-time noninvasive inflammation imaging", Graduate Materials Seminar, University of Texas at Arlington, Arlington, Texas.
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- Past
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June 11, Academic Lecture, Presentation title: "Stem cells in tissue engineering.".
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- Past
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2011, September 9, Presentation title: "Development of nanoprobes for imaging inflammation" Chemistry Department seminar at University of Texas at Dallas, Dallas, Texas.
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- Past
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June 14, Discussion of Techniques, Presentation title: "Tissue engineering scaffolds".
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- Past
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2012, May 8-9, Presentation title: "Novel imaging technology to monitor foreign body reactions in vivo" keynote speaker at the Scandinavian Society for Biomaterials meeting in Uppsala, Sweden.
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- Past
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2010, June 2-4, Distinquished Speaker Series, given 3 separate lectures hosted by College of Life Science, Kaohsiung Medical University, Kaohsiung, Taiwan.
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- Past
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2012, June 22, Presentation title: "Novel approaches for stem cell tissue engineering", invited speaker, National Taiwan University, Department of Chemical Engineering, Taipei, Taiwan.
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- Past
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2012, June 19, Presentation title: "Development of nanoprobes for imaging inflammation", invited speaker, China Pharmaceutical University, Department of Biomedical Engineering, Nanjing, China.
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- Past
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2012, June 18, Presentation title: "Development of nanoprobes for imaging inflammation", invited speaker, National Cheng Kung University, Department of Surgery and Graduate Institute of Biomedical Engineering in Tainan, Taiwan.
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- Past
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2012, June 7, Presentation title: "Novel approaches for stem cell tissue engineering and inflammation imaging", invited speaker, Chang Bing Show Chwan Memorial Hospital, Department of Medical Research and Development in Changhua, Taiwan.
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- Past
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June 3, Presentation title: "Nanodevices for disease diagnosis and drug delivery", Faculty of Medicinal and Applied Chemitry.
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2012, Visiting Chair Professor lecture Series, given 4 Academic Lectures and 3 Technical Discussions hosted by National Changhua Univesity of Education, Changhua, Taiwan.
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- Past
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2012, September 9, Presentation title: "Development of nanoprobes for imaging inflammation" Department of Internal Medicine seminar at University of Texas Southwestern Medical Center, Dallas, Texas.
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- Past
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2011, August 11, Presentation title: "Imaging inflammation", Brown Cancer Institute, University of Louisville, Louisville, Kentucky.
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- Past
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2010, June 24, Presentation title: "Tissue Engineering and Regenerative Medicine", "Austin to Arlington" State Legislators and Staffers Visit, University of Texas at Arlington, Arlington, Texas.
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- Past
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“Novel approach for inducing autologous stem cell-mediated bone”Keynote speaker, The 3rd International Symposium of Materials on Regenerative Medicine, Chang Gung University, Taoyuan County, Taiwan.
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Support & Funding
This data is entered manually by the author of the profile and may duplicate data in the Sponsored Projects section.-
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Sept 2014 to
Present
Tissue-engineered constructs for investigating the effect of lymph node microenvironment on prostate cancer metastasis. sponsored by
US Department of Defense - $553650
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Sept 2014 to
Present
Treating posttraumatic osteoarthritis by promoting autologous stem cell-mediated cartilage regeneration sponsored by
US Department of Defense - $1047359
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Jan 2014 to
Present
Orthopedic Research Scholarship sponsored by
Texas Health Arlington Memorial Hospital - $90000
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Sept 2014 to
Present
Tissue-engineered constructs for investigating the effect of lymph node microenvironment on prostate cancer metastasis. sponsored by
US Department of Defense - $553650
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Sept 2012 to
Present
Modulating and monitoring the foreign body reactions to implants (subcontract) sponsored by
- $201825
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Aug 2012 to
Present
Doctoral training in Department of Bioengineering, University of Texas at Arlington sponsored by
- $399798
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Sept 2012 to
Present
Modulating and monitoring the foreign body reactions to implants (subcontract) sponsored by
- $201825
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Dec 2011 to
Present
Development of cancer traps for prolonging lifespan by eliminating metastatic cancer cells sponsored by
- $200000
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July 2011 to
Present
Creating safe biodegradable photoluminescent implant polymers (Subcontract) sponsored by
- $160000
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Dec 2011 to
Present
Development of cancer traps for prolonging lifespan by eliminating metastatic cancer cells sponsored by
- $200000
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Aug 2010 to
Present
In situ rapidly froming biodegradable hydrogels mediate wound sponsored by
- $196400
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Aug 2010 to
Present
In situ rapidly froming biodegradable hydrogels mediate wound sponsored by
- $196400
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Sept 2008 to
Present
Biomaterial-medaited fibrtoic responses sponsored by
- $1327680
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Sept 2008 to
Present
Biomaterial-medaited fibrtoic responses sponsored by
- $1327680
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Dec 2007 to
Present
In vivo drug release studies in rabbits sponsored by
- $149776
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June 2007 to
Present
Core facility to conduct kidney research sponsored by
- $6000000
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Dec 2007 to
Present
In vivo drug release studies in rabbits sponsored by
- $149776
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Past to
Present
Development of ratiometric imaging probe system for monitoring inflammation (subcontract) sponsored by
- $75490
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Jan 2014 to
Dec 2018
Novel engineered particle platform for endothelium regeneration. sponsored by
University of Texas at Arlington National Institute of Health - $72000
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Sept 2013 to
Aug 2018
Elastic fiber homeostasis in the vaginal wall. sponsored by
University of Texas at Arlington National Institute of Health - $257550
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July 2014 to
June 2016
Bioactive composite cardiac patches engineered from synthetic and tissue-derived components. sponsored by
National American Heart Associate - $40000
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Jan 2014 to
Dec 2015
NIR triggered nano micelles for early diagnosis and targeted therapy of inflammation sponsored by
National Natural Science Foundation of China China Pharmaceutical University - $200000
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July 2014 to
July 2015
Multi-functional particles for stem cell isolation and expansion. sponsored by
University of Texas at Arlington National Institute of Health Progenitec Inc., - $200251
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July 2011 to
June 2015
Creating safe biodegradable photoluminescent implant polymers. sponsored by
University of Texas at Arlington National Institutes for Health - $1250184
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Aug 2013 to
Jan 2015
A novel optical imaging probe system for assessing wound healing and infection. sponsored by
National Institute of Health, - $64338
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Jan 2012 to
Jan 2015
Doctoral Program Enhancement Grant sponsored by
University of Texas at Arlington - $7500
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Dec 2011 to
Dec 2014
Super-high resolution of tumor angiogenesis in deep tissue. sponsored by
Cancer Prevention & Research Institute of Texas (CPRIT) - $30000
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Nov 2010 to
Nov 2013
Pro-inflammatory characteristics of nano-porous alumina. sponsored by
The Swedish Foundation for International Cooperation in Research and Higher Education - $1200000
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July 2010 to
June 2013
Engineering vascular grafts in vivo via orchestrated autologous stem cell responses sponsored by
American Heart Association-South Central Affiliate - $140000
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May 2009 to
Apr 2012
Multifunctional image guided surgical platform sponsored by
National Institute of Health, R21, EB008509-01A2 - $22500
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Sept 2009 to
Aug 2011
Biomaterial-mediated fibrotic responses (administrative supplement sponsored by
National Institute of Health, RO-1, EB007271-01A2S1 - $130195
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Dec 2005 to
Nov 2010
In vivo evaluation of drug delivery formulation (III). sponsored by
Alcon Research Inc., - $95460
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Sept 2008 to
Aug 2009
MRI: Acquisition of a high-resolution transmission electron microscope to enhance interdisciplinary research. sponsored by
National Science Foundation - $320000
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Jan 2008 to
June 2009
Monitoring diabetic retinopathy progression in mice using hyperspectral imaging. sponsored by
MMPC Pilot and Feasibility Program - $66000
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May 2006 to
Jan 2009
Targeted drug delivery nanoparticles for treating uveal melanoma. sponsored by
Advanced Technology Program, Texas Higher Education Coordinating Board - $50000
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Apr 2005 to
Jan 2009
Biocompatibility: Surface initiated biochemistry sponsored by
National Institute of Health, RO-1 - $844063
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Feb 2007 to
Jan 2008
Assessment of anti-neoplastic property of NSAID drugs in vivo sponsored by
Alcon Research Inc. - $35520
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Apr 2007 to
Dec 2007
COE Research Excellence Infrastructure Grant sponsored by
Water Alliance HPLC system - $547455
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July 2002 to
June 2007
Molecular mechanism of biomaterial-mediated fibrotic responses. sponsored by
National American Heart Association, - $300000
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Jan 2005 to
Dec 2005
Prostate Cancer Therapy with Annexin II Nanoparticles sponsored by
Collaborative UNTHSC-UTA Joint Institutional Seed Research Program Award - $10500
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Jan 2005 to
Dec 2005
Target drug delivery magnetic nanospheres for cancer therapy. sponsored by
UTA CBC Collaborative Research Grant - $25000
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Dec 2004 to
Nov 2005
In vivo evaluation of drug delivery formulation (II) sponsored by
Alcon Research Inc. - $166396
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Apr 2003 to
Nov 2005
Nicotine effect on angiogenesis sponsored by
TissueGen Inc. - $44918
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Jan 2001 to
Dec 2004
Eye implant-mediated tissue responses. sponsored by
Advanced Surface Technology Inc. - $20000
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Dec 2003 to
Nov 2004
In vivo evaluation of drug delivery formulation (I). sponsored by
Alcon Research Inc. - $127000
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June 1999 to
July 2004
Foreign body reactions and device-centered infection. sponsored by
National Institute of Health, RO-1, EB-00287 - $943463
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Jan 2000 to
Aug 2002
Timed-release anti-microbial coatings to combat implant-centered infection. sponsored by
Advanced Technology Program, Texas Higher Education Coordinating Board - $25000
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Jan 1998 to
Aug 2000
Bio-mimetic albumin affinity surfaces for biomaterials. sponsored by
Advanced Technology Program Texas Higher Education Coordinating Board - $171530
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Aug 1995 to
July 2000
Phagocyte : surface interactions. sponsored by
National Institute of Health, RO-1 - $601809
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Feb 1997 to
May 2000
Biomaterial-mediated inflammation and fibrosis. sponsored by
National Institute of Health, RO-1 - $673117
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July 1995 to
June 1999
Inflammatory responses to implanted biomaterials. sponsored by
National American Heart Association - $131890
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May 1997 to
Apr 1999
Mechanism of endotracheal tube infection. sponsored by
Baylor Neonatology Section Abbott Grant Award Program - $29602
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Nov 1996 to
May 1997
Adhesion of bacteria and platelets on PVC thoracic catheters. sponsored by
Sherwood Medical Inc. - $7950
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May 1996 to
Aug 1996
SEM studies of the adhesion of platelets on hydrophilic PU umbilical catheter. sponsored by
Sherwood Medical Inc. - $3960
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Dec 1995 to
May 1996
Studies of the p15 peptide in mediating the inflammatory and fibrotic responses to implanted biomaterials in mice. sponsored by
Bard Urological Division - $6623
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Nov 1995 to
May 1996
Studies of acute inflammatory responses to implanted intraocular lenses. sponsored by
Alcon Research Inc. - $9228
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Nov 1995 to
Feb 1996
Chronic inflammatory and fibrotic responses to an implant in rats (Determination of P-15 coupling density). sponsored by
Bard Urological Division - $3568
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Past to
Present
Development of ratiometric imaging probe system for monitoring inflammation (subcontract) sponsored by
- $75490
Patents
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Oct 2013 EFS ID: 17174626 Injectable cancer traps to reduce metastatic cancer
The field of the invention relates generally to the field of cancer. The field of the invention also relates to cancer cell traps and the use thereof for treating and/or preventing cancer metastasis, and for diagnosis and detection of cancer metastasis.
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Oct 2009 7601704 Process for synthesizing oil and surfactant-free hyaluronic acid nanoparticles and microparticles
A method for synthesizing uniformly sized hyaluronic acid ("HA") particles that are substantially free from oil and surfactant contaminants. The method comprises crosslinking HA chains with 1-ethyl-3-(3-dimethlyaminopropyl) carbodiimide hydrochloride ("EDAC") and adipic acid dihydrazide in a water/acetone mixture.
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Other Research Activities
- 2014
- Patent Applications/ Invention Disclosures
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Mar 2014 PENDING PATENT APPLICATIONS
Liping Tang, David Baker. “Adipogenic differentiation method to reduce fibrotic responses”, under reviewed by University of Texas at Arlington, Submitted on March 14, 2014.
Wen-Jing Hu, Liping Tang. “Coating for measuring pH changes”, US 13/905,520 sponsored by Progenitec Inc., Filed on May 30, 2013.
Wen-Jing Hu, Liping Tang. “Oxygen free radical detection”, US 14/515,475, sponsored by Progenitec Inc., Filed on October 15, 2014.
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- Additional Information
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Nov 2014 ABSTRACTS AND POSTERS
Tang L, Eaton JW. Fibrinogen prompts inflammatory responses to implanted biomaterials. Annual Meeting of the American Institute of Chemical Engineers, ‘Cell and protein interactions with biomaterials’ session, November 7-12, 1993, St. Louis, Missouri.
2. Tang L, Tsai C. The biocompatibility of chemical-vapor-deposited diamond. Annual Meeting of the American Institute of Chemical Engineers, ‘Cell and protein interactions with biomaterials’ session, November 7-12, 1993, St. Louis, Missouri.
3. Tang L, Eaton JW. Adsorbed fibrinogen triggers acute inflammatory responses to biomaterials. Clinical Research, 41:164A, 1993.
4. Tang L, Eaton JW. Adsorbed fibrinogen triggers acute inflammatory responses. 27th Annual Hugh Lofland Conference on Arterial Wall Metabolism, Bolton Landing, New York, May 5-7, 1993.
5. Tang L, Eaton JW. Adsorbed fibrinogen-mediated acute inflammatory responses to biomaterials. Transaction of the Society for Biomaterials, 20: 139, 1994.
6. Tang L, Eaton JW. Fibrinogen prompts inflammatory responses to implanted biomaterials. Annual Meeting of Scanning Microscopy International, ‘Cells and Materials’ session, May 7-12, 1994, Toronto, Ontario, Canada.
7. Wang JW, Tang L, Eaton JW. Adsorbed fibrinogen enhances the survival of adherent Staphylococcus epidermidis on implanted biomaterials. First Annual AMC/RPI Joint Research Symposium, Albany Medical College, Albany, New York, March 25, 1995.
8. Tang L, Hough L, Eaton JW. Recruitment of phagocytes to implanted biomaterials is histamine-dependent. Transaction of the Society for Biomaterials, 21: 250, 1995.
9. Su S-H, Tang L, Venezia RA, Eaton JW. Adherence and persistence of antibiotic-sensitive and -resistant Enterococcus faecalis on the surfaces of implanted biomaterials. Second Annual AMC/RPI Joint Research Symposium, Rensselaer Polytechnic Institute, Troy, New York, March 23, 1996.
10. Tang L, Chesney J, Sherry B, Eaton JW. The Pivotal roles of cytokines in the recruitment and adhesion of inflammatory cells to implanted biomaterials. Transactions of the Society for Biomaterials, 23: 127, 1997.
11. Tang L, Welty S, Smith CW, Eaton JW. The participation of adhesion molecules in inflammatory responses to biomaterials. Transactions of the Society for Biomaterials, 23: 261, 1997.
12. Ploplis V, Bussutil S, French E, Tang L, Carmeliet P, Collen D, Plow EF. The inflammatory responses to biopolymer implants in plasminogen deficient mice. XVIth Congress of the International Society on Thrombosis and Haemostasis. Florence, June 6-12, 1997.
13. Ugarova T, Solovjov D, Zhang L, Medved L, Tang L, Plow EF. Proteolysis of fibrinogen regulates its recognition by integrin aMb2. Thrombosis and Haemostatsis. (Suppl.) OC-775, 1997.
14. Tang L, Jennings T, Eaton JW. Mast cells mediate acute inflammatory responses to implanted biomaterials. Annual Meeting of the Society for Pediatric Research, Washington, D.C., May 1997.
15. Lu H, Hughes BJ, Smolen J, Ballantyne CM, Tang L, Beaudet AL, Smith CW. Role of Mac-1 (CD11b/CD18) in neutrophil functions in vivo. Experimental Biology ’97, New Orleans, 1997.
16. Tang L, Sheng Y. The mechanism of device-centered infection. Transaction of the Society for Biomaterials, 24: 17, 1998.
17. Tang L, Wu Y, Timmons RB. Biomaterial surface properties affecting both protein adsorption and host responses. Transaction of the Society for Biomaterials, 24: 273, 1998.
18. Tang L, Eaton JW. Surface protein adsorption and acute inflammatory responses to biomaterials. 10th Symposium on the Material Science and Chemistry of Contact lenses, New Orleans, LA, November 4-6, 1998.
19. Tang L, Eaton JW. Biomaterials-applied biological overview: The origins of evil. Cardiovascular Pathology, 7(5): 286, 1998.
20. Tang L, Jiang W-W, The effect of adsorbed proteins on superoxide production by biomaterial-associated phagocytes. Transaction of the Society for Biomaterials, 25:26, 1999.
21. Tang L, Hu W-J, Wu Y-L, Timmons RB. Surface properties affect the extent of fibrotic responses to implanted biomaterials. Transaction of the Society for Biomaterials, 25:196, 1999.
22. Tang L, Wu Y, Timmons RB. Fibrinogen adsorption and tissue responses to plasma functionalized surfaces. 17th Annual Houston Conference on Biomedical Engineering Research, Houston, TX, February 11-12, page 97, 1999.
23. Jiang W-W, Su S-H, Eberhart RC, Tang L. Phagocyte responses to degradable polymers. Transaction of the Society for Biomaterials, 26:380, 2000.
24. Hu W-J, Eaton JW, Tang L. Molecular basis of biomaterial-mediated foreign body reactions. Transaction of the Society for Biomaterials, 26:403, 2000.
25. Su S-H, Tang L, Meidell RS, Eberhart RC. Curcumin improves the mechanical and biological performance of poly (L-lactic acid) fibers. Transaction of the Society for Biomaterials, 26:944, 2000.
26. Tang L, Hu W-J. Phagocyte: biomaterial interactions. Pittcon 2000. New Orleans, LA, March 12-17, p1186, 2000.
27. Tang L, Jiang W-W. The role of adsorbed proteins on the resistance of implant-associated bacteria. Transaction of the Society for Biomaterials, 27:1, 2001.
28. Su S, Tang L, Meidell R, Landau C, Chao R, Eberhart R. Expandable bioresorbable vascular stent. Transactions of the American Society of Artificial Internal Organs, 47 (2): 169, 2001
29. Su S-H, Landau CE, Chao RYN, Timmons RB, Meidell RS, Tang L, Eberhart RC. Expandable, bioresorbable endovascular stent with anti-platelet and anti-inflammatory treatments. Circulation, 104(17): II-507, 2001
30. Eberhart RC, Su S, Tang L, Chao R, Timmons RB, Meidell RS. An expandable bioresorbable endovascular stent with antiplatelet and anti-inflammatory properties. Transaction of the Society for Biomaterials, 28:10, 2002.
31. Tang L, Hu W, Jiang W. The influence of phagocyte and cytokines on the extent of implant-mediated fibrotic responses. Transaction of the Society for Biomaterials, 28:268, 2002.
32. Tang L, Su S-H, Xiao T-L. Adsorbed fibrin(ogen) triggers posterior capsule opacification in young rabbits. Transaction of the Annual Meeting of the Association for Research in Vision and Ophthalmology, 445, 2002.
33. Nguyen KT, Su S-H, Sheng A, Brouse CF, Greilich PE, Tang L, Eberhart RC. Curcumin and paclitaxel reduce pro-inflammatory tendencies of PLLA fibers for bioadsorbable stents. Transaction of the Society for Biomaterials, 29:78, 2003.
34. Nguyen KT, Su S-H, Sheng A, Brouse CF, Greilich PE, Tang L, Eberhart RC. Curcumin reduces pro-inflammatory tendencies of PLLA fiber in circulating whole blood. Transaction of the Society for Biomaterials, 29:168, 2003.
35. Jiang W-W, Tang L. TNF-α release and MAC-1 upregulation play important roles on the pathogenesis of device-centered infection. Transaction of the Society for Biomaterials, 29:318, 2003.
36. Weng H, Zhou J, Hu Z, Tang L. Tissue responses to temperature sensitive and controlled delivery nanoparticles in eyes. Transaction of the Society for Biomaterials, 29: 131, 2003.
37. Tang L, Weng H, Zhou J, Hu Z. Nanoparticles for intravitreal controlled drug delivery. Transaction of the Annual Meeting of the Association for Research in Vision and Ophthalmology, 4753, 2003.
38. Zdolsek J, Tang L. Fibrinogen and mast cells mediate acute inflammatory responses to implanted biomaterials in human. The Australian and New Zealand Journal of Surgery, 73 (supplement):A271, 2003.
39. Tang L, Weng H, Zhang S, Pang I-H. Differentiation of adult stem cells into retinal cells in vitro and in vivo. Transaction of the Annual Meeting of the Association for Research in Vision and Ophthalmology, 5418, 2004.
40.Patel B, Tang L, Nguyen KT, Cellular uptake of particles in vascular endothelial cells – effects of shear stress. Twelfth International Symposium on Recent Advances in Drug Delivery Systems, February 2005.
41. Koshy A, Weng H, Tang L. Biomaterial implantation prompts the recruitment of stem cells in mice. Transaction of the Society for Biomaterials, 30: 599, 2005
42. Tang L, Zou L. Hydrogel nanoparticles for targeting retinal tissue. Transaction of the Society for Biomaterials, 85, 2006.
43. Manan G, Radhakrishnan H, Tang L, Liu H. Application of near infrared multi-spectral CCD imager to determine the hemodynamic changes in prostate tumor. Proceeding of Biomedical Optics Topical Meeting 2006 (Optics Society of America, Washington DC), paper SH10.
45. Cai T, Li J, Zhang J, Lin A, Marquez M, Tang L, Neogi A, Hu Z. Microgel encapsulated CdTe quantum dots. American Chemical Society 232nd National Meeting (in submission), 2006.
46. Bhattacharyya D, Tang L, Timmons BR. Synthesis and characterization of plasma polymerized thin film hydrogel. American Chemical Society 62nd Southwest Regional Meeting, Houston, Texas October 19-22, 2006.
47. Hu W-J, Tang L. Molecular mechanism of biomaterial-mediated fibrotic responses. National American Heart Research Symposium, Invited presenter, 2006.
48. Uttawar M, Tang L, Aswath P. Tissue regeneration on drug releasing, porous, biodegradable polymer scaffold. Transactions of the Materials Society conference in Biomaterials , 2007.
49.Bhattacharyya D, Susut S, Cho J, Tang L, Timmons RB. Plasma generated polymer films for drug delivery applications. Transactions of the Drug Delivery Society, Invited speaker, July, 2007.
50. Tang L, Wu L, Ong M, Howe WE, Lin VK. Human lens epithelial cells possess stem cell like property. Transaction of the Annual Meeting of the Association for Research in Vision and Ophthalmology, D849, 2008.
Yang J, Tang L, Nguyen K, Chiao J-C. Novel biodegradable elastomers and scaffold-sheet tissue engineering. Transaction of 16th International Conference on Mechanics in Medicine and Biology. Pittsburgh, PA, 23th-25th July, 2008.
Yang J, Dey J, Thevenot P, Tang L, Nguyen KT. Novel biodegradable elastic polymers and scaffold-sheet tissue engineering strategy. Society for Biomaterials Translational Research Symposium. Atlanta, GA, September 11-13, 2008.
Thevenot PT, Javed A, Lotfi P, Antich P, Tang L. In vivo SDF-1α (CXCL12) mediated MSC recruitment to tissue engineering scaffold. TERMIS NA 2008, 505, 2008.
Thevenot PT, Nair A, Sohaebuddin S, Tang L. Scaffold treatment with SDF-1α (CXCL12) diminishes the immune response. TERMIS NA-2008, 502, 2008.
Gautam S, Liu L, Zhang Y, Dey J, Chen W, Mason RP, Tang L, Zhang C, Zheng J, Guleserian KJ, Yang J. Aliphatic biodegradable photoluminescent polymers. 2008 Cancer Imaging Program Symposium, Dallas, TX, November 13th-14th, 2008.
Mathew J, Kache V, Liu C, Tang L, Yang J. Nano-featured highly interconnective macroporous elastic scaffolds for cardiovascular tissue engineering. UT Metroplex Day, Dallas, 2008
57. Hansen RH III, Shen J, Tang L. Localized recruitment of multipotent mesenchymal stem cells by biomaterial implants. Transaction of the Society for Biomaterials, 45, 2009.
59. Nair A, Yang J, Tang L. Novel porous scaffold for releasing bioactive molecules. Transaction of the Society for Biomaterials, 58, 2009.
60. Lotfi P, Koshy A, Shen J, Tang L. Biomaterial-mediated recruitment of stem and progenitor cells. Transaction of the Society for Biomaterials, 145, 2009.
61. Kona S, Wavhal D, Timmons R, Tang L, Nguyen KT. In vitro evaluation of plasma surface-modified PLGA nanoparticles. Transaction of BMES, 2009.
62. Vadla A, Kona S, Wavhal D, Timmons R, Tang L, Nguyen KT. Surface functionalized biodegradable nanoparticles in cancer cells. Transaction of BMES, 2009.
63. Tang L, Tsai Y-T, Hu, W. Three-dimensional model for quantifying nanoparticle drug delivery in eyes. Transaction of the Annual Meeting of the Association for Research in Vision and Ophthalmology 5963/A586, 2009.
64. Ko C-Y, Wu L, Tang L. Melanoma cell recruitment induced by biomaterial-mediated inflammation involves in CCR7/CCL21 lymphatic pathway. 12th SCBA International Symposium 2009.
Zhang Y, Tang L, Yang J. Novel biodegradable aliphatic photoluminescent polymers. BMES Annual Fall Meeting, Pittsburgh, PA. Oct. 7-10, 2009.
Tran RT, Gyawali D, Thevenot P, Tang L, Yang J. A Biodegradable Elastomer Featuring a Dual Crosslinking Mechanism. ASAIO's 55th Annual Conference for The American Society for Artificial Organs, 2009.
Yang J, Zhang Y, Gautam S, Liu L, Mason R, Tang L. Novel Biodegradable Fluorescent Polymers for Biomedical Applications. The 4th WACBE World Congress on Bioengineering, Hong Kong, China, July 26-29, 2009.
Zhang Y, Gautam S, Liu L, Dey J, Tran RT, Gyawali D, Chen W, Mason RP, Tang L, Zheng J, Guleserian KJ, Yang J. Biodegradable photoluminescent polymeric biomaterials. 2009 UT Metroplex day, Arlington, Texas, March 6, 2009.
Tran T, Gyawali D, Thevenot P, Tang L, Yang J. A Biodegradable Elastomer Featuring a Dual Crosslinking Mechanism. ASAIO's 55th Annual Conference for the American Society for Artificial Organs (2009 ASAIO-IFAO), Dallas, Texas, May 28-30, 2009.
Yang J, Gautam S, Liu L, Zhang Y, Dey J, Chen W, Mason RP, Tang L, Zhang C, Zheng J, Guleserian KJ. Development of novel aliphatic biodegradable fluorescent polymers for tissue engineering. The 27th Scientific Conference of the Society for Physical Regulation in Biology and Medicine (SPRBM), Oahu, Hawaii, Jan. 6-9, 2009.
Su J, Gonzales HP, Todorov M, Kojouharov H, Tang L. A mathematical model for foreign body reactions, preliminary report, in 105st AMS meeting, Baylor University, Waco, Texas, Oct 16-18, 2009, program, by American Mathematical Society, page 61.
Lin Z-J, Alexandrakis G, Patel NL, Shen J, Tang L, and Liu H. "Time-gated optical imaging to detect positive prostate cancer margins," in SPIE Photonics West (San Jose, CA, 2009), pp. 716119-1-9.
Kona S, Xu H, Tsai Y-T, Dong J-F, Tang L, Nguyen K. Multi-ligand nanoparticles for targeted drug delivery to endothelium after cardio-interventions. BMES 2010 conference, 9-1-14-B, Austin, Texas.
Wadajkar A, Rajan P, Bhavsar Z, Koppolu B, Zhang Y, Cui W, Tang L, Yang J, Nguyen K. Theranostic nanoparticles for cancer diagnosis and treatment. BMES 2010 conference, 7B-7-86, Austin, Texas.
Nair A, Shen J, Sun M-W, Zhang A, Tang L. Biomaterial implant recruits and differentiates autologous stem cells. BMES 2010 conference, 8A-19-247, Austin, Texas.
Tsai Y-T, Hu W-J, Tang L. Three-dimensional quantification and visualization model for drug delivery in eyes. BMES 2010 conference, 8B-2-18, Austin, Texas.
Ko C-Y, Nair A, Tsai Y-T, Zhou J, Tang L. Development of cancer traps for eliminating metastatic cancer cells in vivo. BMES 2010 conference, 9A-6-80, Austin, Texas.
Aphale N, Xu H, Gyawali D, Wadajkar A, Tang L, Yang J, Nguyen K. In situ composite hydrogel system for treatment of complex wounds. BMES 2010 conference, 7B-7-92, Austin, Texas.
Zhou J, Tsai Y-T, Weng H, Tang L. Novel near-infrared fluorescence (NIR) nanoprobes for in vivo imaging of inflammatory diseases. BMES 2010 conference, OP-9-1-16-B, Austin, Texas.
Zhou J, Tsai Y-T, Weng H, Tang L. Noninvasive monitoring of implant-mediated inflammatory responses by detecting reactive oxygen species in vivo. Transaction of the Society for Biomaterials, 175, 2011.
Nair A, Shen J, Tsai Y-T, Tang L. Orchestrated stem cell-based regeneration (OSCeR) for bone tissue engineering, Transaction of the Society for Biomaterials, 896, 2011.
Nair A, Shen J, Tran RT, Guleserian K, Yang J, Tang L. Engineering vascular grafts via orchestrated autologous progenitor cell responses. 27th Southern Biomedical Engineering Conference, OP:T6, SE 1.5, 2011. International Journal of Medical Implants and Devices, 5(2): 63, 2011.
Su L, Tran R, Tsai Y, Tang L, Yang J, Nguyen KT. In situ re-endothelialization via multifunctional urethane-doped polyester (UPE) nanoscaffold. 27th Southern Biomedical Engineering Conference, OP:T6, SE 3.2, 2011. International Journal of Medical Implants and Devices, 5(2): 87, 2011.
Baker DW, Liu X, Weng H, Luo C, Tang L. Fibroblast/fibrocyte: surface interaction dictates tissue reactions to micropillar implants. 27th Southern Biomedical Engineering Conference, OP:T6, SE 4.2, 2011. International Journal of Medical Implants and Devices, 5(2):99, 2011.
Aphale NV, Xu H, Wadajkar A, Gyawali DR, Tang L, Yang J, Nguyen KT. In situ composite hydrogel system for treatment of complex wounds. 27th Southern Biomedical Engineering Conference, OP:T6, SE 4.3, 2011. International Journal of Medical Implants and Devices, 5(2): 99, 2011.
Zhou J, Tsai Y, Weng H, Baker D, Tang L. New nanoprobes for assessing foreign body reactions in vivo. 27th Southern Biomedical Engineering Conference, OP:T5, SE 5.5, 2011. International Journal of Medical Implants and Devices, 5(2): 111, 2011.
Su, J, Yang J, Perkins L, Todorov M, Tang L. Predictive tools for foreign body fibrotic reactions using 2-Dimensional computational model. 27th Southern Biomedical Engineering Conference, OP:T1, SE 2.4, 2011. International Journal of Medical Implants and Devices, 5(2): 65, 2011.
Ferraz N, Hoess A, Thormann A, Heilmann A, Shen J, Tang L, Ott MK. Role of alumina nanoporosity in acute cell responses. European Cells and Materials. 21: suppl. 1, 16, 2011.
Tsai Y-T, Zhou J, Weng H, Tang L. Development of near-infrared nanoprobes for in vivo monitoring of fibrin deposition and inflammatory responses. American Heart Association Annual Conference, 2011, AOS.707.02 section, 15950.
Zhou J, Tsai Y-T, Weng H, Tang EN, Baker D, Tang L. Development of nanoprobes for imaging foreign body reactions. European Cells and Materials 23 Suppl 5, page 3 2012.
Zhou J, Tsai Y-T, Weng H, Nair A, Tang L. Novel near-infrared probe for in vivo detection of biomaterial-mediated neutrophil responses. 9th World Biomaterials Congress, 2012.
Tsai Y-T, Zhou J, Weng H, Tang L. Real-time noninvasive in vivo imaging of foreign body reactions using pH ratiometric fluorescence probes. 9th World Biomaterials Congress, 2012.
Montoya I., Zhou J, Tang L, Word R.A. Development of thermosensitive nanoparticles hydrogel for protein delivery in connective tissues of the pelvic floor. 2012 33rd Annual American Urogynecologic Society Conference, 2012.
Zhou J, Tsai, Y-T, Weng H, Tang EN, Baker D, Tang L. Development of nanoprobes for imaging foreign body reactions. European Cells and Materials, 23(suppl. 5): 3, 2012.
Nguyen KT, Xie Z, Su L-C, Xu H, Kona S, Tang L, Dong J-F, Barnerjee S, Yang J. Biomimetic multi-functional nanoparticles for treatment of cardiovascular diseases. BMES 2012 conference, 2012.
Nair AM, Shen J, Tsai Y-T, Sun X, Saxena R, Tang L. Erythropoietin enhances osteogenic differentiation of autologous stem cells in critical size defects. BMES 2012 conference, 2012.
Ko C-K, Wu L, Nair AM, Tsai Y-T, Lin VK, Tang L. Development of cancer traps using tissue engineering scaffolds. BMES 2012 conference, 2012.
Ko C-K, Wu L, Nair AM, Tsai Y-T, Lin VK, Tang L. Development of cancer traps for eliminating metastatic melanoma cells. CPRIT conference, 2012.
Montoya I, Acevedo JF, Word RA, Tsunezumi J, Yanagisawa H, Zhou J, Tang L. Development of thermosensitive nanoparticle hydrogel for protein delivery in connective tissues of pelvic floor. The 33rd Annual Scientific Meeting of the American Urogynecologic Society. October 3-6, 2012. Chicago, Illinois, USA. Female Pelvic Med Reconstr Surg. 2012 Sep-Oct;18(5 Suppl 2):S47-219.
Zhou J, Hao G, Weng H, Tsai Y-T, Baker DW, Sun X, Tang L. In vivo evaluation of device-associated inflammation using positron emission tomography imaging. Transaction of the Society for Biomaterials, #71, 2013.
Baker DW, Zhou J, Tsai Y-T, Weng H, Tang EN, Tang L. Development of novel imaging probes for the detection of polarized macrophage subsets during foreign body reactions. Transaction of the Society for Biomaterials, #354, 2013.
Baker DW, Zhou J, Tsai Y-T, Weng H, Tang L. Monitoring polarized macrophages to illuminate inflammation and the role of fibrocytes in the foreign body responses to biomaterial implants. (in press) Biomaterial Day, University of Texas at Austin, May 31, 2013.
Xie Z, Liu L, Weng H, Mason R, Tang L, Nguyen KN, Yang J. Label-free fluorescent biodegradable polylactones. BMES 2013 conference, OP-Sat-2-2, 2013.
Tsai Y-T, Zhou J, Weng H, Tang EN, Baker D, Tang L. Development of a novel imaging probe for early detection of foreign body reactions. BMES 2013 conference, P-Fri-B-119, 2013.
Xie Z, Paras CB, Punnakitikashem P, Weng H, Su L-C, Vu K, Tang L, Yang J, Nguyen KT. Antibacterial nanofibrous mesh-A wound healing device for complex wound treatment. BMES 2013 conference, P-Fri-A-186, 2013.
Montoya TI, Acevedo JF, Keller PW, Zhou J, Tang L, Word RA, Wai CY. Myogenic stem cell-laden hydrogel scaffold improves contractile properties of the disrupted external anal sphincter in an animal model. 2013 Annual American Urogynecologic Society Conference, 2013.
Zhou J, Weng H, Tsai Y-T, Tang L. Development of a novel optical probe for in vivo detection of biomaterial-mediated apoptosis. Transaction of the Society for Biomaterials, #367, 2014.
Wu J, Ding Q, Troung D, Weng H, Tang, L, Hong Y. An injectable porcine cartilage-derived hydrogel for cartilage repair and regeneration. Transaction of the Society for Biomaterials, #507, 2014.
Nair A, Shen J, Yang J, Guleserian, Zhang C, Tang L. Development of tissue engineered small diameter vascular grafts employing autlogous stem cells. Transaction of the Society for Biomaterials, #624, 2014.
Pandey N, Wadajkar AS, Sundaresan V, Hernandez E, Heish J-T, Tang L, Yang J, Nguyen KT. Thermo-responsive, multimodel imagining enabled nanoparticles toward cancer therapy (Drug delivery track). BMES 2014 conference, P (accepted).
Tang EN, Nair A, Baker D, Hu W, Tang L, Zhou J. In vivo imaging of wound infection using a bacteria-targeting optical nanoprobe (Biomedical Imaging and optics). BMES 2014 conference, P783.
Zhou J, Weng H, Nair A, Hu W, Tang L. Development of ROS ratiometic optical nanoprobes for in vivo imaging of wound inflammation (Biomedical Imaging and optics). BMES 2014 conference, P389.
Nair A, Shen J, Zhang CC, Saxena R, Borrelli J, Tran R, Yang J, Tang L. Tissue regeneration using scaffold-mediated autologous progenitor cell responses in vivo (Tissue engineering track). BMES 2014 conference, P385.
PATENT APPLICATIONS:
Zhibing Hu, Xiaohu Xia, Liping Tang. “Process for synthesis of oil and surfactant-free hyaluronic acid nanoparticles and microparticles”. US Patent #7601704. October 13th, 2009
Liping Tang. “Injectable cancer traps to reduce metastatic cancer”, EFS ID: 17174626 sponsored by University of Texas at Arlington, Submitted on October 2013.
Liping Tang, David Baker. “Adipogenic differentiation method to reduce fibrotic responses”, under reviewed by University of Texas at Arlington, Submitted on March 14, 2014.
Wen-Jing Hu, Liping Tang. “Coating for measuring pH changes”, US 13/905,520 sponsored by Progenitec Inc., Filed on May 30, 2013.
Wen-Jing Hu, Liping Tang. “Oxygen free radical detection”, US 14/515,475, sponsored by Progenitec Inc., Filed on October 15, 2014.
RESEARCH FUNDINGS
Active Supports
As the Principle Investigator
Department of Defense, 2013 Prostate Cancer Research Program, Ideal Development Award - Established Investigator, $553,650, 9/1/2014-8/31/2017, Principal Investigator, Tissue-engineered constructs for investigating the effect of lymph node microenvironment on prostate cancer metastasis.
Department of Defense, Congressionally Directed Medical Research Programs, 2013 Peer Reviewed Orthopaedic Research Program, Translational Research Award, $1,047,359, 9/1/2014-8/31/2017, Principal Investigator, Treating posttraumatic osteoarthritis by promoting autologous stem cell-mediated cartilage regeneration.
Texas Health Arlington Memorial Hospital, Orthopedic Research Scholarship, $90,000 ($30,000/year for 3 years), 1/1/2014-12/31/201 6.
National Natural Science Foundation of China, Research Fund of International Young Scientists, RMB $200,000, January 1, 2014 – December 31, 2015, Principal Investigator, NIR triggered nano micelles for early diagnosis and targeted therapy of inflammation, sponsored by the China Pharmaceutical University, Nanjing, China.
As a Co- Investigator and/or Subcontractor
National Institute of Health, 1 RO1 EB-012575-01 $180,000 (subcontract) 7/11/2011 – 6/30/2015, Co-Investigator (PI: Jian Yang, $1,250,184), Creating safe biodegradable photoluminescent implant polymers.
National Institute of Health, RO-1, HL118498-01A1, $72,000 (sub-award), 1/1/2014 - 12/31/2018, Co-Investigator, (PI: Kytai Nguyen, $955,161), Novel engineered particle platform for endothelium regeneration.
National Institute of Health, RO-1, AG028048-06, $257,550 (subcontract), 09/1/2013 - 8/31/2018, Co-Investigator, (PI: Ann Word, $1,631,391), Elastic fiber homeostasis in the vaginal wall.
National American Heart Associate, Beginning Investigator Award, $40,000 (subcontract), 07/1/2014 - 6/30/2016, Co-Investigator, (PI: Yi Hong, $140,000), Bioactive composite cardiac patches engineered from synthetic and tissue-derived components.
Cancer Prevention & Research Institute of Texas, $30,000 (sub-award), 12/15/2011 - 12/14/2014, Co-Investigator (PI: Baohong Yuan, $1,092,035), Super-high resolution of tumor angiogenesis in deep tissue.
University of Texas at Arlington, Doctoral Program Enhancement Grant, $7,500, 1/17/2012- 1/28/2015, Co-Investigator, PI: Khosrow Behbehani, Biomedical Engineering Doctoral Program Enhancement Plan.
Department of Education, P200A120234, $399,798 ($133,266/year), 8/16/2012 – 8/15/2015, Co-Investigator, Project Director: Khosrow Behbehani, Doctoral training in Department of Bioengineering, University of Texas at Arlington.
National Institute of Health, R43 AR064650-01A1, $64,338 (subcontract), 8/1/2013 – 1/31/2015, Subcontract - Principal Investigator (Progenitec Inc., $199,918; PI: Wenjing Hu), A novel optical imaging probe system for assessing wound healing and infection.
National Institute of Health, O’Brien Kidney Center, $6,000,000, 6/1/2007 – 5/31/2018, Co-Investigator (PI: Peter Igarashi, UTSW), Core facility to conduct kidney research.
National Institute of Health, R41 MH106303-01, 7/11/2014 – 7/10/2015, Co-Investigator (Progenitec Inc., $200,251; PI: Wenjing Hu), Multi-functional particles for stem cell isolation and expansion.
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- Patent Applications/ Invention Disclosures
Students Supervised
- Doctoral
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Present
Ashley Dacy -
Present
Yi-Hui Huang -
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Aug 2010
Ashwin M Nair Senior Lecturer & Undergraduate Faculty Advisor, Department of Bioengineeringanair@uta.edu | (817) 272-6250 -
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- Master's
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Sept 2013
Miriam Moctezuma -
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Nov 2006
Vijay Rajaram -
Nov 2006
Geetha Merkala -
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Nov 2005
Swaroopa Shreeram Vaidya -
Nov 2005
Anju Koshy -
May 2005
Anju Koshy -
Nov 2004
Kajal Shukla -
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Nov 2004
Dhyani Jayasundara -
Nov 2004
Deena Thomas -
Nov 2004
Dhara Purohit -
Nov 2004
Nishat Mohammed Shaikh -
Sept 2002
Ammar Adam -
Sept 2002
Jasmine Saba
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- Undergraduate Honor's Thesis
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Present
Jennifer Dela Pena
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Peers Mentored
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Hong Weng hongweng@uta.edu | (817) 272-75232002-2004 & 2009-2014, Research topic: “Tissue responses to hydrogel particles”, currently employed as Research Associate at University of Texas at Arlington, Arlington, Texas
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Jinghui Shen 2004-2013, Postdoctoral Research Associate, Research topic: “Engineering tissue scaffold for promoting In situ stem cell tissue regeneration”, currently employed as a Laboratory Manager at the University of Texas Southwestern Medical Center at Dallas,
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Ashwin M Nair Senior Lecturer & Undergraduate Faculty Advisor, Department of Bioengineeringanair@uta.edu | (817) 272-62502011-2013, Postdoctoral Research Associate, Research subject: “Functionalized scaffold for stem cell tissue engineering.” currently employed as a Senior Lecturer at the Bioengineering Department of UTA, Arlington, Texas.
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Ling Zou lzou@uta.edu | (817) 272-75232004-2009, Research topic: “Development of controlled release devices for treating eye diseases”, currently employed as Attending Physician and Associate Professor at ShenZhenEyeHospital, ShenZhen, China.
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Lanxiao Wu lanxiao@uta.edu | (817) 272-75232005-2008, Research topic: “Development of animal model to study molecular mechanism of cancer metastasis”, currently leading a startup clinical diagnosis company at Beijing, China
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Sheng Zhang 2002-2004, Research topic: “Novel stem cell therapy and differentiation cocktails”, currently employed as Research Associate at Baylor College of Medicine, Houston, Texas.
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Kytai Nguyen Professor of Bioengineeringknguyen@uta.edu | (817) 272-25402002-2003, Research topic: “Hydrogel nanoparticles drug delivery”, currently employed as Associate Professor at Bioengineering Department, Arlington, Texas.
Courses
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BE 5364-005
TISSUE ENGINEERING LECTUREProvide broad and basic knowledge related to the designs, research and medical applications in tissue engineering.
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BE 1105-005
Medical Applications of EngineeringIntroduction to basic biology and engineering problems associated with living systems and health care delivery. Examples will be used to illustrate how basic concepts and tools of science & engineering can be brought to bear in understanding, mimicking and utilizing biological processes.
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BE 5365-005
Tissue Engineering LaboratoryIntroduction to laboratory techniques commonly used for culturing, growing, and analyzing cells and tissues, image processing, and scaffold fabrication methods with a focus on the mechanisms and applications of 3D printing technology.
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BE 5364-005
TISSUE ENGINEERING LECTUREProvide broad and basic knowledge related to the designs, research and medical applications in tissue engineering.
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BE 1105-005
Medical Applications of EngineeringIntroduction to basic biology and engineering problems associated with living systems and health care delivery. Examples will be used to illustrate how basic concepts and tools of science & engineering can be brought to bear in understanding, mimicking and utilizing biological processes.
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BE 5365-005
Tissue Engineering LaboratoryIntroduction to laboratory techniques commonly used for culturing, growing, and analyzing cells and tissues.
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BE 5364-005
TISSUE ENGINEERING LECTUREIntroduce basic knowledge related to the designs and issues associated with a variety of tissue engineering applications. Acquire the necessary knowledge, design logic, and research techniques to work on tissue engineering products and implantable medical devices.
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BE 5365-005
Tissue Engineering LaboratoryIntroduction to Laboratory techniques commonly used for culturing, growing, and analyzing cells and tissues. Students will learn the necessary skills required for maintaining and analyzing cells in culture. Students will develop laboratory techniques related to cell assays and cell staining. Students will be introduced to concepts of designing in vitro tissue engineering products.
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BE 5365-005
Tissue Engineering LaboratoryIntroduction to Laboratory techniques commonly used for culturing, growing, and analyzing cells and tissues. Students will learn the necessary skills required for maintaining and analyzing cells in culture. Students will develop laboratory techniques related to cell assays and cell staining. Students will be introduced to concepts of designing in vitro tissue engineering products.
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BE 5365-005
Tissue Engineering LaboratoryIntroduction to Laboratory techniques commonly used for culturing, growing, and analyzing cells and tissues. Students will learn the necessary skills required for maintaining and analyzing cells in culture. Students will develop laboratory techniques related to cell assays and cell staining. Students will be introduced to concepts of designing in vitro tissue engineering products.
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BE 5364-005
TISSUE ENGINEERING LECTUREIntroduce basic knowledge related to the designs and issues associated with a variety of tissue engineering applications. Acquire the necessary knowledge, design logic, and research techniques to work on tissue engineering products and implantable medical devices.
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Service to the Community
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Appointed
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Sept 2009 to June 2013 Board of Trustee Member, Fort Worth Regional Science and Engineering Fair
Not for profit Science Fair organiation affiliated to ISEF
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Aug 2009 to July 2012 Director, Forth Worth Regional Science and Engineering Fair
Texas ERC 11, Fort Worth, Texas.
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Apr 2002 to Apr 2003 Director, Biotechnology Thrust
Chinese Institute of Engineers Dallas/Fort Worth Chapter, Dallas, Texas.
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Service to the Profession
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Appointed
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Apr 2003 to Present National Institute of Health, study section member
Surgery and bioengineering study section, biomaterials and biointerface study section, innate immunity and inflammation study section, nanotechnology, biomaterials for tissue engineering and gene delivery, small business innovative research study section, Transformative research award, National Cancer Institute special emphasis panel, -
Apr 2014 to Present Editorial Board - Frontier in Biomaterials
A specialty section of Frontiers in Bioengineering and Biotechnology and Materials (Frontiers Open Assess Publisher)
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Apr 2013 to Present Editorial Board - International Journal of Cancer Studies and Research
Sci Doc Publisher
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May 2012 to Present Editorial Board Member, Journal of Biochips & Tissue Chips
OMICS Publishing Group
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Apr 2011 to Present Editorial Board Member, Journal of Bioterrorism and Biodefense
OMICS Publishing Group
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Apr 2012 to Present Editorial Board Member, Journal of Development Biology and Tissue Engineering
Acadmic Journals
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Apr 2011 to Present Associate Editor, Reviews in Nanoscience and Nanotechnology
American Scientific Publishers
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Apr 2012 to Present Editorial Board, The Scientific World Journal
Hindawi Publishing Corp.
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Apr 2007 to Apr 2010 Study section member, Tobacco-related disease research program
University of California
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June 2003 to June 2008 Study section member - American Heart Association
Biotechnology and Bioengienering study section, Western 1B, Lung, Respiration, Resusciation, Immunology & Microbiology, Surgery study section, Bioengineering and Biotechnology study section,
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Apr 2010 to Apr 2010 Invited Grant Reviewer, Netherlands Organisation for Scientific Research
ECHO-Project grant
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Jan 2012 to Present Kentucky Lung Cancer Research Program, external reviewer
University of Louisville,
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Elected
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Apr 2012 to Present Steering Committee Member of International College of Fellows - Biomaterials Science and Engineering
The honorary status of "Fellow, Biomaterials Science and Engineering" (FBSE) was established in April 1992 after the constituent biomaterials societies of the World Biomaterials Congress, now the IUS-BSE, recognized the need for the public recognition of those of their members who have gained a status of excellent professional standing and high achievements in the field of biomaterials science and engineering.
Fellows are accomplished members and role models in the field of biomaterials science and engineering. Fellows are expected, through word and deed, to foster the field of biomaterials and to support its professional development as a practical and intellectual endeavour.
New Fellows are announced and recognised at World Biomaterials Congresses.
The duly nominated, approved, confirmed, and installed fellow has the right to carry the letters FBSE. These letters indicate the national recognition and international respect of his/her comprehension of professional issues and accomplishments as a scientist or engineer in the field of biomaterials science and engineering.
The fellow status is awarded for life.
A Fellow has all rights and obligations of an active member of their Society.
It is expected that Fellows shall recognise individual achievements and contributions to the practice of BSE, foster professional interactions of BSE practitioners among each other, and with medical practitioners, patients, regulatory and legislative offices, and the public, promote public awareness of the profession of BSE, and promote and encourage professional and continuing education in BSE. -
Apr 2013 to Apr 2013 Proposal Reviewer, Agency for Science, Research & Technology (A*STAR) in Singapore
Proposal reviewer
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Service to the University
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Appointed
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Apr 2002 to Apr 2005 Member, College of Engineering Ethic Committee
University of Texas at Arlington, Arlington, Texas.
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Apr 2004 to Apr 2005 Member, College of Engineering Award Committee
University of Texas at Arlington, Arlington, Texas.
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Apr 2006 to Apr 2007 Chair, Nano Bio cluster hiring committee (Search for five faculty in all ranks), College of Engineering
University of Texas at Arlington, Arlington, Texas.
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Apr 2006 to Apr 2009 Member, College of Engineering Scholarship Committee
University of Texas at Arlington, Arlington, Texas.
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Apr 2001 to Apr 2009 Member, Radiation Safety Committee
University of Texas at Arlington, Arlington, Texas,
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Apr 2010 to Apr 2012 Member, Animal Care Facility Users Committee
University of Texas at Arlington, Arlington, Texas.
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Sept 2004 to June 2013 Track advisors, Biomaterials and Tissue Engineering Track, Bioengineering Department,
University of Texas at Arlington, Arlington, Texas.
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Apr 2009 to Present Track advisor, 5-year Biochemistry (BS) and Biomedical Engineering (MS) fast track, Bioengineering Department Track advisor, 5-year Biochemistry (BS) and Biomedical Engineering (MS) fast track, Bioengineering Department
University of Texas at Arlington, Arlington, Texas.
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Sept 2001 to Present Member, Institutional Animal Care and Use Committee
University of Texas at Arlington, Arlington, Texas.
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Sept 2001 to Present Chair, Institutional Biosafety Committee
University of Texas at Arlington, Arlington, Texas.
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Other
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Nov 2002 to Present Thesis Committee Member
Angela Fayann Boreneman M.S. in Biomedical Engineering, 2002, thesis title: "Release kinetics: Degradation rates: mechanical properties of PLLA and PLGA wet extruded fibers.”
Manish Dalwani M.S. in Biomedical Engineering, 2002, thesis title: “Automated Interpretation of functional brain images".
Rajeshkumar Dhamodharasamy M.S. in Biomedical Engineering, 2002, thesis title: “Automation of peptide array”.
Robert Balog Ph.D. in Biomedical Engineering, 2003, thesis title: “Digital optical chemistry (DOC) a novel method for DNA oligonucleotide microarray fabrication”.
Arthur Braden Ph.D. in Biomedical Engineering, 2003, thesis title: “Synthesis of novel gene therapy carrier”.
Mridula Vishwanath M.S. in Biomedical Engineering, 2003, thesis title: “Role of RHO and Rac in the mechanical response of corneal fibroblasts to changes in local matrix stress”.
Riyaz Mehta M.S. in Biomedical Engineering, 2004, thesis title: “Flow cytometry based analysis of CD8+ T-cell functions in multiple sclerosis”.
Brent Crow Ph.D. in Biomedical Engineering, 2004, thesis title: “Development and assay of a novel hydrogel-cored PLLA fiber for delivery of neurotrophins”.
Anusha Sricharan M.S. in Biomedical Engineering, 2006, thesis title: “Phenotypic difference in the behavior of immortalized human bronchial epithelial cells in three dimensional culture systems”.
Manan Goel M.S. in Biomedical Engineering, 2006, thesis title:”Application of NIR CCD imager to monitor hemodynamic changes in prostate tumor and efficacy of chemotherapy”.
Atul Sathe M.S. in Biomedical Engineering, 2006, thesis title:”Anti-immune therapy for organ transplantation”.
Ebrahim Bengali M.S. in Biomedical Engineering, 2006, thesis title: “Design and test of a three-dimensional in-vitro assay for the segregation of nociceptive and proprioceptive sensory axons”.
Mayur Uttarwar M.S. in Biomedical Engineering, 2006, thesis title: “Novel techniques of fabricating porous biodegradable polymer scaffolds for sustaining drug release”.
Asif Rizwan M.S. in Biomedical Engineering, 2006, thesis title: “Miniature optical coherence tomography probe”.
Nicole L Conaway Ph.D. inBiology, 2007, thesis topic: “Novel mast cell membrane receptors”.
Kim Shabi Ph.D. inBiology, 2007, thesis topic: “Therapeutic efficacy of cancer and virus killing polymers”.
Dhiman Bhattacharyya Ph.D. inChemistry and Biochemistry, 2008, thesis title: “Material properties and host responses”.
Danielle Miller Ph.D. in Biomedical Engineering, 2008, thesis topic: “3D patterning of collagen tissue scaffold”.
Areum Kim, Ph.D. inBiomedical Engineering, 2008, thesis title: “Corneal keratinocytes in responding to biomechanical stimulation”.
Yi Guo, M.S. inBiomedical Engineering, 2008, thesis title: “Development of iron oxide based nanoparticles as dual-modality imaging probes”.
Peiying Liu, Ph.D., inBiomedical Engineering, 2008, thesis title: “Evaluating bone by ultrasound”.
Yevgeniya Le, Ph.D., in Pathology and Laboratory Medicine, 2009, thesis title: “Immunocamouflage: The biophysical and biological basis of immunoprotection by grafted methoxypoly(ethylene glycol)” invited as external reviewer by The University of British Columbia, Vancouver, Canada.
Pavitra Chakravarty, Ph.D., inBiomedical Engineering, 2010, thesis title: “Targeted delivery of carbon nanotubes to cancer cells”.
Hao Xu, M.D., Ph.D., inBiomedical Engineering, 2010, thesis title: “Enhanced endothelialization on surface modified poly (L-lactic acid)”.
Soujanya Kona, Ph.D., inBiomedical Engineering, 2010, thesis title: “Multi-ligand nanoparticles for targeted drug delivery to the vascular endothelium”.
Zarna Bhavsar, M.S., inBiomedical Engineering, 2010, thesis title: “Development of magnetic-based core-shell nanoparticles for drug delivery application in melanoma skin cancer”.
Parvathi Nair, M.S., inBiomedical Engineering, 2010, thesis title: “A novel injectable porous hydrogel composite scaffold for bone tissue engineering”.
Swarup Narayan Dash, B.S., Ph.D. exam II, 2011, thesis title: “Pleiotrophin mediated nerve regeneration across long gap peripheral nerve defects and spinal cord contusion injury”.
Allison Carroll Case, Ph.D., inBiomedical Engineering, 2012, thesis title: “A novel platform to generate synthetic vaccine candidates”.
Chengxin Zhou, Ph.D. exam II, 2012, thesis title: “Novel 3-D culture models for investigating the migratory mechanics of both activated and quiescent corneal keratocytes”.
Swarup Narayan Dash, Ph.D. inBiomedical Engineering, 2012, thesis title: “Pleiotrophin enhance nerve regeneration across long gap peripheral nerve defect.”.
Sonia Santimano, M.S., inBiomedical Engineering, 2012, thesis title: “Development of magnetic based multi-layer microparticles for stem cell isolation, enrichment and detachment.”.
Aniket Sharadrao Wadajkar, Ph.D. inBiomedical Engineering, 2012, thesis title: “Design and application of magnetic-based theranostic nanoparticles for prostate cancer management.”.
Alicia Prieto Langarica, Ph.D. inMathematics, 2012, thesis title: “From Discrete to continuous models of cell movement: An application to medical implants.”.
Yi Zhang, Ph.D. inBiomedical Engineering, 2012, thesis title: “Methodology of citric acid based functional biomaterial development and application.”.
Lee-Chun Su, M.S. in Biomedical Engineering, 2012, thesis title: “Antimicrobial properties of citric acid based polymers.".
Sarita Bhetawal, M.S. in Biomedical Engineering, 2012, thesis title: “Evaluation of tissue responses from the regenerative multielectrode array (REMI) implant using ATF-3 and cJUN.".
Princy K Prasad, M.S. in Biomedical Engineering, 2012, thesis title: “Study of a log gap nerve injury in a rabbit common peroneal nerve model.".
Mohammadreza Mehdizadeh, Ph.D. in Material Science and Engineering, 2012, thesis title: “Syntheses, characterization, and applications of injectable citrate-based mussel-inspired biodegradable adhesive (iCMBA) polymers and hydrogels.”.
Srikanth Vasudevan, Ph.D. in Biomedical Engineering, 2013, thesis title: “Long gap peripheral nerve reconstruction using decelluarized nerve grafts.”.
Chengxin Zhou, Ph.D. in Biomedical Engineering, 2013, thesis title: “The functional roles of RHO-kinase and matrix metalloproteinases in regulating corneal stromal cell mechanics in 3-D collagen matrices.”.
Homa Homayoni, Ph.D. in Biomedical Engineering, 2013, thesis title: “Protoporphysin IX (PPIX)-conjugated self-lighting nanoparticles for photodynamic therapy: synthesis and characterization.”.
Jyothi Unnikrishna Menon, Ph.D. in Biomedical Engineering, 2014, thesis title: “Polymeric nano/microparticles for management of pulmonary diseases.”.
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Administrative Appointment
- 2013
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June 2013 to June 2015 - interim chair, University of Texas at Arlington bioengineering Dept
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